Preparation and structure of pyrrolo- and isoindoloquinazolinones

P. Sohár, A. Csámpai, Angela E. Szabó, G. Stájer

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Aroylpropionic acids react with cis- and trans-2-aminocyclohexane- or 4-cyclohexene-1-carboxamides and diexo-norbornane/ene analogues to give saturated or partly saturated pyrroloquinazolinones and methylene-bridged derivatives. In the reactions of 2-formylbenzoic acid or 2-aroylbenzoic acid with aminocarboxamides, the isoindoloquinazolinones were formed. Bisacyl derivatives were also isolated. The product aminocarboxamides always retained their starting cis, trans, diexo or diendo configurations. The structures, including the ring annelations and the position of the aryl group or, for the reaction of formylbenzoic acid, that of the H atom on the new chiral centre, were established by means of NMR spectroscopy.

Original languageEnglish
Pages (from-to)139-147
Number of pages9
JournalJournal of Molecular Structure
Volume694
Issue number1-3
DOIs
Publication statusPublished - Jun 2004

Fingerprint

preparation
acids
Acids
Norbornanes
Derivatives
Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
methylene
Atoms
analogs
nuclear magnetic resonance
rings
products
configurations
spectroscopy
atoms
2'-disulfonic acid 1-amino-8-nephthol-2
cyclohexene

Keywords

  • Diastereomers
  • DIFFNOE
  • Isoindoloquinazolinones
  • NMR
  • Pyrroloquinazolinones

ASJC Scopus subject areas

  • Structural Biology
  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Atomic and Molecular Physics, and Optics

Cite this

Preparation and structure of pyrrolo- and isoindoloquinazolinones. / Sohár, P.; Csámpai, A.; Szabó, Angela E.; Stájer, G.

In: Journal of Molecular Structure, Vol. 694, No. 1-3, 06.2004, p. 139-147.

Research output: Contribution to journalArticle

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