Preparation and structure of cycloalkane‐condensed [1,3]thiazino[3,2‐a] pyrimidinones

P. Sohár, Zsolt Szöke‐Molnár, G. Stájer, G. Bernáth

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21 Citations (Scopus)

Abstract

Isocyanate salts prepared from cis‐2‐amino‐1‐cyclopentane‐ and ‐hexane‐carboxylate and the corresponding trans‐cyclohexane and ‐cyclohexene derivates with KSCN were cyclized to cycloalkane/ene‐condensed 2‐thioxo‐4‐pyrimidinones, which were transformed to tricyclic 1,3‐thiazino[3,2‐a]pyrimidinones by addition of dimethyl acetylenedicarboxylate. The stereo structures of the new compounds were established by IR and 1H and 13C NMR spectroscopy, making use of the signal multiplicities in the proton‐coupled carbon spectra.

Original languageEnglish
Pages (from-to)959-963
Number of pages5
JournalMagnetic Resonance in Chemistry
Volume27
Issue number10
DOIs
Publication statusPublished - 1989

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Keywords

  • C NMR
  • H NMR
  • Configuration and conformation
  • Tricyclic cycloalkane/ene‐fused [1,3]thiazino[3,2‐a]pyrimidinones

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)

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