Preparation and characterization of perforated SERS active array for particle trapping and sensitive molecular analysis

István Rigó, Miklós Veres, Tamás Váczi, Eszter Holczer, Orsolya Hakkel, András Deák, Péter Fürjes

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Agold-coated array of flow-through inverse pyramids applicable as substrate for entrapment and immobilization of micro-objects and for surface enhanced Raman spectroscopic measurements was fabricated using bulk micromachining techniques from silicon. Surface morphology, optical reflectance, immobilization properties, and surface enhanced Raman amplification of the array were modelled and characterized. It was found that the special perforated periodic 3D structure can be used for parallel particle and cell trapping and highly sensitive molecular analysis of the immobilized objects.

Original languageEnglish
Article number93
JournalBiosensors
Volume9
Issue number3
DOIs
Publication statusPublished - Sep 2019

Keywords

  • Bulk micromachining
  • FDTD
  • Particle/cell entrapment
  • SERS array
  • Surface enhanced Raman spectroscopy

ASJC Scopus subject areas

  • Clinical Biochemistry

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