Biocompatible chitosan has been successfully modified by condensation reaction using natural di- and tricarboxylic acids, as crosslinking agents to form particles. Clear or opalescent stable colloid systems were fabricated in aqueous medium. Average size of swelled crosslinked chitosan macromolecules was about 300 nm and the size of dried particles was about 200 nm. The size was independent of the hydrophilic character of the crosslinkers and the ratio of crosslinking.
|Journal||Muanyag Es Gumi/Plastics and Rubber|
|Publication status||Published - Aug 1 2005|
ASJC Scopus subject areas
- Polymers and Plastics