Abstract
Changes of long term potentiation (LTP) as an elementary learning model in the first generation offspring of fumonisin B 1 (FB 1) treated pregnant rats were studied. Prenatal exposition to FB 1 caused marked and significant alterations and anomalies in in vitro brain slice bioelectric activity. This is the first study to use in vitro rat cortex slices as biosensors monitoring LTP changes in offspring after FB 1 exposition of pregnant rats, and providing evidence for brain functional bioelectric anomalies of neurodevelopmental origin caused by mycotoxin FB 1.
| Original language | English |
|---|---|
| Pages (from-to) | 1947-1950 |
| Number of pages | 4 |
| Journal | Cereal Research Communications |
| Volume | 36 |
| Issue number | SUPPL. 5 |
| DOIs | |
| Publication status | Published - 2008 |
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Keywords
- Developmental risks
- Developmental toxicity
- Fumonisin B
- In vitro biotests
- LTP
- Rat cortex slice
ASJC Scopus subject areas
- Agronomy and Crop Science
- Genetics
- Physiology
Cite this
Prenatal dietary fumonisin B 1 exposure may modify learning processes in rat offspring. / Banczerowski-Pelyhe, Ilona; Banczerowski, Péter; Varró, Petra; Világi, I.
In: Cereal Research Communications, Vol. 36, No. SUPPL. 5, 2008, p. 1947-1950.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prenatal dietary fumonisin B 1 exposure may modify learning processes in rat offspring
AU - Banczerowski-Pelyhe, Ilona
AU - Banczerowski, Péter
AU - Varró, Petra
AU - Világi, I.
PY - 2008
Y1 - 2008
N2 - Changes of long term potentiation (LTP) as an elementary learning model in the first generation offspring of fumonisin B 1 (FB 1) treated pregnant rats were studied. Prenatal exposition to FB 1 caused marked and significant alterations and anomalies in in vitro brain slice bioelectric activity. This is the first study to use in vitro rat cortex slices as biosensors monitoring LTP changes in offspring after FB 1 exposition of pregnant rats, and providing evidence for brain functional bioelectric anomalies of neurodevelopmental origin caused by mycotoxin FB 1.
AB - Changes of long term potentiation (LTP) as an elementary learning model in the first generation offspring of fumonisin B 1 (FB 1) treated pregnant rats were studied. Prenatal exposition to FB 1 caused marked and significant alterations and anomalies in in vitro brain slice bioelectric activity. This is the first study to use in vitro rat cortex slices as biosensors monitoring LTP changes in offspring after FB 1 exposition of pregnant rats, and providing evidence for brain functional bioelectric anomalies of neurodevelopmental origin caused by mycotoxin FB 1.
KW - Developmental risks
KW - Developmental toxicity
KW - Fumonisin B
KW - In vitro biotests
KW - LTP
KW - Rat cortex slice
UR - http://www.scopus.com/inward/record.url?scp=80053090475&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80053090475&partnerID=8YFLogxK
U2 - 10.1556/CRC.36.2008.Suppl.3
DO - 10.1556/CRC.36.2008.Suppl.3
M3 - Article
VL - 36
SP - 1947
EP - 1950
JO - Cereal Research Communications
JF - Cereal Research Communications
SN - 0133-3720
IS - SUPPL. 5
ER -