Prenatal diagnosis of a giant congenital primary cerebral hemangiopericytoma

Gábor Sobel, Judit Halász, Katalin Bogdányi, István Szabó, Katalin Borka, Péter Molnár, Zsuzsa Schaff, Ferenc Paulin, Ferenc Bánhidy

Research output: Contribution to journalArticle

13 Citations (Scopus)


Congenital primary intracranial hemangiopericytomas are exceptionally rare tumors. We present a case of a fetus, with the prenatal sonogram at 33 weeks of gestation revealing a large cerebral tumor. Because of the enlarged head, a cesarean section was performed. The tumor was confirmed by postnatal ultrasound, magnetic resonance imaging (MRI) and biopsy. Elevated intracranial pressure and hemorrhage led to death on the 11th day. Autopsy revealed a 10×9 cm large inhomogeneous tumor located centrally, mainly in the posterior fossa. Histology showed a hypercellular and hypervascular tumor with extended necrosis and high mitotic rate. The tumor cells were positive for vimentin and CD34 antigens and negative for several neurological markers, desmin and CD31. The diagnosis of a congenital primary cerebral hemangiopericytoma was confirmed.

Original languageEnglish
Pages (from-to)46-49
Number of pages4
JournalPathology and Oncology Research
Issue number1
Publication statusPublished - May 1 2006


  • Congenital brain tumors
  • Infantile hemangiopericytoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Oncology
  • Cancer Research

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