The analgesic effect of calcitonin (MiacalcicR; Calcitonin-SandozR) was studied in 12 patients with bone metastases under double-blind conditions. 100 MRC units or placebo were injected subcutaneously daily for 28 days. The results indicated the high analgesic potency of calcitonin in advanced bone metastases. It is claimed that calcitonin may act by a mechanism different from the restoration of the altered bone stucture. Endocrinological studies are planned to elucidate the mode of action of the drug.
|Number of pages||9|
|Journal||Clinical Trials Journal|
|Publication status||Published - Dec 1 1983|
- Advanced malignancy
- analgesic effect
ASJC Scopus subject areas
- Pharmacology (medical)