Preliminary observations on the analgesic effect of salmon calcitonin in osteolytic metastases

J. Szántó, J. Sándor

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Abstract

The analgesic effect of calcitonin (MiacalcicR; Calcitonin-SandozR) was studied in 12 patients with bone metastases under double-blind conditions. 100 MRC units or placebo were injected subcutaneously daily for 28 days. The results indicated the high analgesic potency of calcitonin in advanced bone metastases. It is claimed that calcitonin may act by a mechanism different from the restoration of the altered bone stucture. Endocrinological studies are planned to elucidate the mode of action of the drug.

Original languageEnglish
Pages (from-to)266-274
Number of pages9
JournalClinical Trials Journal
Volume20
Issue number5
Publication statusPublished - Dec 1 1983

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Keywords

  • Advanced malignancy
  • analgesic effect
  • calcitonin

ASJC Scopus subject areas

  • Pharmacology (medical)

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