The pregnancy of women suffering from a chronic renal disease presents a special challenge both to the obstetrician- gynaecologist and the nephrologist. Pregnancy may lead to the progression of the kidney disease, and this progression can occasionally be marked. The most important predictors of an impairment in the renal function are the severity of the renal failure, hypertension during pregnancy and the degree of proteinuria. Pregnancy of patients with kidney disease may be associated with a number of maternal and foetal obstetrical complications the most common of which are preeclampsia, intrauterine growth retardation and premature delivery. The risk of obstetrical complications is directly proportional to the severity of the renal failure and the degree of hypertension. In systemic lupus erythematosus, pregnancy-associated immunological changes and the presence of certain autoantibodies must be considered as further risk factors. In diabetic nephropathy, the metabolic control has a specific and significant impact on pregnancy outcome, in addition to the renal failure itself. The author presents the major points to be considered during the management of the pregnancy of patients with renal disease, and the current guidelines to the administration of antihypertensive drugs during pregnancy.
|Translated title of the contribution||Pregnancy complicated with hypertension developing on the basis of an underlying-renal disease|
|Number of pages||8|
|Journal||Magyar Noorvosok Lapja|
|Publication status||Published - Mar 19 2009|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology