Preeclampsia is associated with decreased serum α2-HS glycoprotein (fetuin-A) concentration

A. Molvarec, L. Kalabay, Zoltán Derzsy, András Szarka, Amrita Halmos, Balázs Stenczer, Philippe Arnaud, I. Karádi, Z. Prohászka, J. Rigó

Research output: Contribution to journalArticle

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Abstract

The purpose of this study was to determine serum α2-HS glycoprotein (AHSG) concentration and its diagnostic accuracy in preeclampsia. In this case-control study, the serum C-reactive protein (CRP) and AHSG levels were measured in 93 preeclamptic patients and in 127 healthy pregnant women by immunoturbidimetry and radial immunodiffusion. The serum CRP levels were significantly higher, whereas the serum AHSG concentrations were significantly lower in the preeclamptic group than in the control group (median (25th to 75th percentile), CRP: 6.71 mg l-1 (2.76-12.69) vs. 3.38 mg l-1 (1.69-7.27), respectively; AHSG: 660 μg ml-1 (612-768) vs. 744μg ml-1 (660-816), respectively; P-1) was significantly associated with preeclampsia (adjusted odds ratio (95% confidence interval): 3.69 (1.82-7.51); P

Original languageEnglish
Pages (from-to)665-669
Number of pages5
JournalHypertension Research
Volume32
Issue number8
DOIs
Publication statusPublished - 2009

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alpha-2-HS-Glycoprotein
Pre-Eclampsia
C-Reactive Protein
Glycoproteins
Blood Proteins
Serum
Immunodiffusion
Case-Control Studies
Pregnant Women
Odds Ratio
Confidence Intervals
Control Groups

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Preeclampsia is associated with decreased serum α2-HS glycoprotein (fetuin-A) concentration. / Molvarec, A.; Kalabay, L.; Derzsy, Zoltán; Szarka, András; Halmos, Amrita; Stenczer, Balázs; Arnaud, Philippe; Karádi, I.; Prohászka, Z.; Rigó, J.

In: Hypertension Research, Vol. 32, No. 8, 2009, p. 665-669.

Research output: Contribution to journalArticle

Molvarec, A. ; Kalabay, L. ; Derzsy, Zoltán ; Szarka, András ; Halmos, Amrita ; Stenczer, Balázs ; Arnaud, Philippe ; Karádi, I. ; Prohászka, Z. ; Rigó, J. / Preeclampsia is associated with decreased serum α2-HS glycoprotein (fetuin-A) concentration. In: Hypertension Research. 2009 ; Vol. 32, No. 8. pp. 665-669.
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AU - Szarka, András

AU - Halmos, Amrita

AU - Stenczer, Balázs

AU - Arnaud, Philippe

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