A terápiás válasz prediktív tényezoi krónikus vírushepatitisekben

Translated title of the contribution: Predictors of response to treatment in chronic viral hepatitis

Research output: Contribution to journalArticle

Abstract

As the results of antiviral therapy for hepatitis B and C infections are still suboptimal, attention has been given to the strategies to maximize the effectiveness of currently available therapeutic modalities. In this approach, individualized management - based on predictive factors that influence response to treatment - is a key component. The paper summarizes how predictors can assist in optimizing therapy of patients with chronic viral hepatitis. In chronic hepatitis B, a favorable response to interferon or nucleoside/ nucleotide therapy can be expected in young, HBeAg-positive patients with alanine aminotransferase (ALT) values >2-5x upper limit of normal, histological activity >4-10, HBV DNA 5 copies/ml (1 log 10 decrease in HBV DNA titer or a titer of

Original languageHungarian
Pages (from-to)841-846
Number of pages6
JournalLege Artis Medicinae
Volume18
Issue number12
Publication statusPublished - Dec 2008

Fingerprint

Chronic Hepatitis
Therapeutics
Hepatitis B e Antigens
DNA
Chronic Hepatitis B
Hepatitis C
Hepatitis B
Alanine Transaminase
Nucleosides
Interferons
Antiviral Agents
Nucleotides
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A terápiás válasz prediktív tényezoi krónikus vírushepatitisekben. / Pár, A.

In: Lege Artis Medicinae, Vol. 18, No. 12, 12.2008, p. 841-846.

Research output: Contribution to journalArticle

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