Predicting the time needed to achieve steady state if absorption and elimination constants are equal

Júlia Singer, L. Vereczkey

Research output: Contribution to journalArticle

Abstract

A simple table is derived to facilitate the rapid estimation of the number of close administrations needed to achieve a certain fraction of the steady-state plasma concentration in the case of one-compartment model with uniform multiple oral dosing and equal absorption and elimination constants.

Original languageEnglish
Pages (from-to)297-300
Number of pages4
JournalJournal of Pharmacokinetics and Biopharmaceutics
Volume27
Issue number3
Publication statusPublished - 1999

Keywords

  • Absorption
  • Achieving steady state
  • Elimination
  • Equal

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

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abstract = "A simple table is derived to facilitate the rapid estimation of the number of close administrations needed to achieve a certain fraction of the steady-state plasma concentration in the case of one-compartment model with uniform multiple oral dosing and equal absorption and elimination constants.",
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KW - Elimination

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