Prealbumin as a hapten carrier protein in certain varieties of dermatitis

S. Husz, J. Hunyadi, A. Dobozy, Anna Sz Kenderessy, Éva Szabó, Nikolaus Simon

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A significant decrease of serum prealbumin levels and an increased proportion of prealbumin bearing lymphocytes in peripheral blood have been found in patients of hapten-induced diseases. Prealbumin deposition in the vessel walls, and/or prealbumin positive cells (granulocytes, lymphocytes, macrophages) in the dermis have been observed in patients with proved drug allergy as well as allergic contact dermatitis using immunofluorescence technique. The eluates from membrane of lymphocytes of patients with drug allergy contained a mitogenic substance, probably antigen and sometimes prealbumin as well. These results also support the earlier suggested hypothesis that the prealbumin may act as a hapten carrier protein.

Original languageEnglish
Pages (from-to)357-364
Number of pages8
JournalArchives of Dermatological Research
Volume264
Issue number3
DOIs
Publication statusPublished - Jan 1979

Fingerprint

Prealbumin
Haptens
Dermatitis
Carrier Proteins
Drug Hypersensitivity
Lymphocytes
Allergic Contact Dermatitis
Dermis
Granulocytes
Fluorescent Antibody Technique
Macrophages
Antigens
Membranes
Serum

Keywords

  • Elution from membrane of lymphocytes
  • Hapten carrier protein
  • Prealbumin

ASJC Scopus subject areas

  • Dermatology

Cite this

Prealbumin as a hapten carrier protein in certain varieties of dermatitis. / Husz, S.; Hunyadi, J.; Dobozy, A.; Kenderessy, Anna Sz; Szabó, Éva; Simon, Nikolaus.

In: Archives of Dermatological Research, Vol. 264, No. 3, 01.1979, p. 357-364.

Research output: Contribution to journalArticle

Husz, S. ; Hunyadi, J. ; Dobozy, A. ; Kenderessy, Anna Sz ; Szabó, Éva ; Simon, Nikolaus. / Prealbumin as a hapten carrier protein in certain varieties of dermatitis. In: Archives of Dermatological Research. 1979 ; Vol. 264, No. 3. pp. 357-364.
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