Pre- and postsynaptic effects of eugenol and related compounds on Helix pomatia L. neurons

J. Szabadics, L. Erdelyi

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

We showed how eugenol blocks the synaptic transmission and gave a possible interpretation how it inhibits the excitation-contraction coupling that several authors described previously [3, 9]. Eugenol acts both in the pre- and postsynaptic side of the neurons. It blocks the Ca2+-currents, decreases the membrane potential of the neurons, increases the inward resistance and decreases the GABA, ACh and glutamate evoked excitatory responses in submillimolar concentration.

Original languageEnglish
Pages (from-to)265-273
Number of pages9
JournalActa Biologica Hungarica
Volume51
Issue number2-4
Publication statusPublished - 2000

Fingerprint

Helix pomatia
Eugenol
eugenol
contraction
Neurons
neurons
membrane
Excitation Contraction Coupling
synaptic transmission
membrane potential
Synaptic Transmission
glutamates
Membrane Potentials
gamma-Aminobutyric Acid
Glutamic Acid
Membranes
calcium
effect

Keywords

  • Eugenol
  • Helix pomatia
  • Identified neurons
  • Membrane effects
  • Neurotransmitters

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Pre- and postsynaptic effects of eugenol and related compounds on Helix pomatia L. neurons. / Szabadics, J.; Erdelyi, L.

In: Acta Biologica Hungarica, Vol. 51, No. 2-4, 2000, p. 265-273.

Research output: Contribution to journalArticle

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