Newborn foals at birth are practically agammaglobulinaemic and depend on the maternal immunity originating from the colostral immunoglobulins (IG) at the first hours of life. Maximum absorption occurs within 8 hours after foaling. It is ideal, if the foal suckles at least half of the 2 liters of colostrum until this time. In order to decrease the occurrence of hypogammaglobulinaemic cases, it is worth measuring the serum concentration of the IgG with rapidly obtainable, semi quantitative, easy performable ELISA tests (SNAP, CITE) around 8 to 12 hours of life. The radial immunodiffusion, the zinc-sulphate turbidity, the latex agglutination or the quantitative IgG test can also be used. Colostrum with at least 3000 mg/dl IgG concentration and 1,06 g/dl specific gravity is recommended to use. By this way 800 mg/dl serum IgG concentration can be obtained. If the IgG concentration between 8-12 hours after birth is lower than expected, high quality colostrum can be used orally. After 24 hours of life hyperimmune plasma or lyophilized equine IgG can only be administrated by intravenously in order to increase the serum IgG concentration. In order to prevent newborn foal losses, it is very important to measure the IgG levels between 8-12 hours of life and supplement the missing amounts of immunoglobulins in time. Different types of passive transfer flailures are also discussed.
|Translated title of the contribution||Practical aspects of the immunoglobulin supply state in newborn foals. Literature review|
|Number of pages||9|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Jan 1 2005|
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