PR Interval identifies clinical response in patients with non-left bundle branch block a multicenter automatic defibrillator implantation trial-cardiac resynchronization therapy substudy

Valentina Kutyifa, Martin Stockburger, James P. Daubert, Fredrik Holmqvist, Brian Olshansky, Claudio Schuger, Helmut Klein, Ilan Goldenberg, Andrew Brenyo, Scott McNitt, B. Merkely, Wojciech Zareba, Arthur J. Moss

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Background :In Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADITCRT), patients with non-left bundle branch block (LBBB; including right bundle branch block, intraventricular conduction delay) did not have clinical benefit from cardiac resynchronization therapy with defibrillator (CRT-D). We hypothesized that baseline PR interval modulates clinical response to CRT-D therapy in patients with non-LBBB.Methods and Results :Non-LBBB patients (n=537; 30%) were divided into 2 groups based on their baseline PR interval as normal (including minimally prolonged) PR (PR

Original languageEnglish
Pages (from-to)645-651
Number of pages7
JournalCirculation: Arrhythmia and Electrophysiology
Volume7
Issue number4
DOIs
Publication statusPublished - Aug 1 2014

Fingerprint

Cardiac Resynchronization Therapy
Defibrillators
Bundle-Branch Block
Therapeutics

Keywords

  • Atrioventricular block
  • Cardiac resynchronization therapy
  • Defibrillators
  • Heart failure
  • Implantable
  • Mortality

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Medicine(all)

Cite this

PR Interval identifies clinical response in patients with non-left bundle branch block a multicenter automatic defibrillator implantation trial-cardiac resynchronization therapy substudy. / Kutyifa, Valentina; Stockburger, Martin; Daubert, James P.; Holmqvist, Fredrik; Olshansky, Brian; Schuger, Claudio; Klein, Helmut; Goldenberg, Ilan; Brenyo, Andrew; McNitt, Scott; Merkely, B.; Zareba, Wojciech; Moss, Arthur J.

In: Circulation: Arrhythmia and Electrophysiology, Vol. 7, No. 4, 01.08.2014, p. 645-651.

Research output: Contribution to journalArticle

Kutyifa, Valentina ; Stockburger, Martin ; Daubert, James P. ; Holmqvist, Fredrik ; Olshansky, Brian ; Schuger, Claudio ; Klein, Helmut ; Goldenberg, Ilan ; Brenyo, Andrew ; McNitt, Scott ; Merkely, B. ; Zareba, Wojciech ; Moss, Arthur J. / PR Interval identifies clinical response in patients with non-left bundle branch block a multicenter automatic defibrillator implantation trial-cardiac resynchronization therapy substudy. In: Circulation: Arrhythmia and Electrophysiology. 2014 ; Vol. 7, No. 4. pp. 645-651.
@article{8dc38c5814d14eebb827913e78f8ae34,
title = "PR Interval identifies clinical response in patients with non-left bundle branch block a multicenter automatic defibrillator implantation trial-cardiac resynchronization therapy substudy",
abstract = "Background :In Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADITCRT), patients with non-left bundle branch block (LBBB; including right bundle branch block, intraventricular conduction delay) did not have clinical benefit from cardiac resynchronization therapy with defibrillator (CRT-D). We hypothesized that baseline PR interval modulates clinical response to CRT-D therapy in patients with non-LBBB.Methods and Results :Non-LBBB patients (n=537; 30{\%}) were divided into 2 groups based on their baseline PR interval as normal (including minimally prolonged) PR (PR",
keywords = "Atrioventricular block, Cardiac resynchronization therapy, Defibrillators, Heart failure, Implantable, Mortality",
author = "Valentina Kutyifa and Martin Stockburger and Daubert, {James P.} and Fredrik Holmqvist and Brian Olshansky and Claudio Schuger and Helmut Klein and Ilan Goldenberg and Andrew Brenyo and Scott McNitt and B. Merkely and Wojciech Zareba and Moss, {Arthur J.}",
year = "2014",
month = "8",
day = "1",
doi = "10.1161/CIRCEP.113.001299",
language = "English",
volume = "7",
pages = "645--651",
journal = "Circulation: Arrhythmia and Electrophysiology",
issn = "1941-3149",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - PR Interval identifies clinical response in patients with non-left bundle branch block a multicenter automatic defibrillator implantation trial-cardiac resynchronization therapy substudy

AU - Kutyifa, Valentina

AU - Stockburger, Martin

AU - Daubert, James P.

AU - Holmqvist, Fredrik

AU - Olshansky, Brian

AU - Schuger, Claudio

AU - Klein, Helmut

AU - Goldenberg, Ilan

AU - Brenyo, Andrew

AU - McNitt, Scott

AU - Merkely, B.

AU - Zareba, Wojciech

AU - Moss, Arthur J.

PY - 2014/8/1

Y1 - 2014/8/1

N2 - Background :In Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADITCRT), patients with non-left bundle branch block (LBBB; including right bundle branch block, intraventricular conduction delay) did not have clinical benefit from cardiac resynchronization therapy with defibrillator (CRT-D). We hypothesized that baseline PR interval modulates clinical response to CRT-D therapy in patients with non-LBBB.Methods and Results :Non-LBBB patients (n=537; 30%) were divided into 2 groups based on their baseline PR interval as normal (including minimally prolonged) PR (PR

AB - Background :In Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADITCRT), patients with non-left bundle branch block (LBBB; including right bundle branch block, intraventricular conduction delay) did not have clinical benefit from cardiac resynchronization therapy with defibrillator (CRT-D). We hypothesized that baseline PR interval modulates clinical response to CRT-D therapy in patients with non-LBBB.Methods and Results :Non-LBBB patients (n=537; 30%) were divided into 2 groups based on their baseline PR interval as normal (including minimally prolonged) PR (PR

KW - Atrioventricular block

KW - Cardiac resynchronization therapy

KW - Defibrillators

KW - Heart failure

KW - Implantable

KW - Mortality

UR - http://www.scopus.com/inward/record.url?scp=84907875596&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907875596&partnerID=8YFLogxK

U2 - 10.1161/CIRCEP.113.001299

DO - 10.1161/CIRCEP.113.001299

M3 - Article

C2 - 24963007

AN - SCOPUS:84907875596

VL - 7

SP - 645

EP - 651

JO - Circulation: Arrhythmia and Electrophysiology

JF - Circulation: Arrhythmia and Electrophysiology

SN - 1941-3149

IS - 4

ER -