Potentiometric and spectroscopic study of nickel(II) and cobalt(II) complexes of histamine-containing dipeptides

T. Gajda, Bernard Henry, Jean Jacques Delpuech

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The formation and structure of cobalt(II) and nickel(II) complexes of glycylhistamine (Gly-Hist) and sarcosylhistamine (Sar-Hist) have been studied by pH-metric and 1H-NMR methods. An EPR study of the analogous, diamagnetically diluted copper(II) complex is also included. In the pH range 3-9. monomeric 1:1 and 1:2. more or less deprotonated complexes are formed (MLH, ML, MLH-1, MLH-1(OH), ML2, ML2H-1, M = Co(II), Ni(II)) depending on the pH and metal-to-ligand ratio. The interaction between ligands and nickel(II) at pH > 9 was characterized by the formation of imidazole-bridged (through both N1 and N3 nitrogens) polynuclear species (NiLH-2)n, with {4N} coordinated metal centers. In the case of Gly-Hist, the 1H-NMR study showed the existence of a single oligomeric (probably tetrameric, n = 4) species, while the steric hindrance of the N-CH3 group in Sar-Hist produces a series of coexisting oligomers, with n ≥ 4.

Original languageEnglish
Pages (from-to)2455-2460
Number of pages6
JournalInorganic Chemistry
Volume34
Issue number9
Publication statusPublished - 1995

Fingerprint

histamines
Dipeptides
Cobalt
Nickel
Histamine
cobalt
Metals
Nuclear magnetic resonance
nickel
Ligands
Oligomers
Paramagnetic resonance
Copper
Nitrogen
nuclear magnetic resonance
ligands
imidazoles
oligomers
metals
nitrogen

ASJC Scopus subject areas

  • Inorganic Chemistry

Cite this

Potentiometric and spectroscopic study of nickel(II) and cobalt(II) complexes of histamine-containing dipeptides. / Gajda, T.; Henry, Bernard; Delpuech, Jean Jacques.

In: Inorganic Chemistry, Vol. 34, No. 9, 1995, p. 2455-2460.

Research output: Contribution to journalArticle

@article{1e644491afb0495db0a66cce2872e589,
title = "Potentiometric and spectroscopic study of nickel(II) and cobalt(II) complexes of histamine-containing dipeptides",
abstract = "The formation and structure of cobalt(II) and nickel(II) complexes of glycylhistamine (Gly-Hist) and sarcosylhistamine (Sar-Hist) have been studied by pH-metric and 1H-NMR methods. An EPR study of the analogous, diamagnetically diluted copper(II) complex is also included. In the pH range 3-9. monomeric 1:1 and 1:2. more or less deprotonated complexes are formed (MLH, ML, MLH-1, MLH-1(OH), ML2, ML2H-1, M = Co(II), Ni(II)) depending on the pH and metal-to-ligand ratio. The interaction between ligands and nickel(II) at pH > 9 was characterized by the formation of imidazole-bridged (through both N1 and N3 nitrogens) polynuclear species (NiLH-2)n, with {4N} coordinated metal centers. In the case of Gly-Hist, the 1H-NMR study showed the existence of a single oligomeric (probably tetrameric, n = 4) species, while the steric hindrance of the N-CH3 group in Sar-Hist produces a series of coexisting oligomers, with n ≥ 4.",
author = "T. Gajda and Bernard Henry and Delpuech, {Jean Jacques}",
year = "1995",
language = "English",
volume = "34",
pages = "2455--2460",
journal = "Inorganic Chemistry",
issn = "0020-1669",
publisher = "American Chemical Society",
number = "9",

}

TY - JOUR

T1 - Potentiometric and spectroscopic study of nickel(II) and cobalt(II) complexes of histamine-containing dipeptides

AU - Gajda, T.

AU - Henry, Bernard

AU - Delpuech, Jean Jacques

PY - 1995

Y1 - 1995

N2 - The formation and structure of cobalt(II) and nickel(II) complexes of glycylhistamine (Gly-Hist) and sarcosylhistamine (Sar-Hist) have been studied by pH-metric and 1H-NMR methods. An EPR study of the analogous, diamagnetically diluted copper(II) complex is also included. In the pH range 3-9. monomeric 1:1 and 1:2. more or less deprotonated complexes are formed (MLH, ML, MLH-1, MLH-1(OH), ML2, ML2H-1, M = Co(II), Ni(II)) depending on the pH and metal-to-ligand ratio. The interaction between ligands and nickel(II) at pH > 9 was characterized by the formation of imidazole-bridged (through both N1 and N3 nitrogens) polynuclear species (NiLH-2)n, with {4N} coordinated metal centers. In the case of Gly-Hist, the 1H-NMR study showed the existence of a single oligomeric (probably tetrameric, n = 4) species, while the steric hindrance of the N-CH3 group in Sar-Hist produces a series of coexisting oligomers, with n ≥ 4.

AB - The formation and structure of cobalt(II) and nickel(II) complexes of glycylhistamine (Gly-Hist) and sarcosylhistamine (Sar-Hist) have been studied by pH-metric and 1H-NMR methods. An EPR study of the analogous, diamagnetically diluted copper(II) complex is also included. In the pH range 3-9. monomeric 1:1 and 1:2. more or less deprotonated complexes are formed (MLH, ML, MLH-1, MLH-1(OH), ML2, ML2H-1, M = Co(II), Ni(II)) depending on the pH and metal-to-ligand ratio. The interaction between ligands and nickel(II) at pH > 9 was characterized by the formation of imidazole-bridged (through both N1 and N3 nitrogens) polynuclear species (NiLH-2)n, with {4N} coordinated metal centers. In the case of Gly-Hist, the 1H-NMR study showed the existence of a single oligomeric (probably tetrameric, n = 4) species, while the steric hindrance of the N-CH3 group in Sar-Hist produces a series of coexisting oligomers, with n ≥ 4.

UR - http://www.scopus.com/inward/record.url?scp=0001085131&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0001085131&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0001085131

VL - 34

SP - 2455

EP - 2460

JO - Inorganic Chemistry

JF - Inorganic Chemistry

SN - 0020-1669

IS - 9

ER -