Az ionofor coccidiumellenes szerek potenciálása duokvinnal - A Cryptosporidium baileyivel szembeni hatékonyság házityúkban

Másodközlés

Translated title of the contribution: Potentiation of ionophorous anticoccidials with duokvin - Efficacy against Cryptosporidium baileyi in chickens. Second communication

I. Varga, T. Sréter, Békési László

Research output: Contribution to journalArticle

Abstract

Three battery tests, employing 444 Arbor Acres chickens, were conducted to study the anticryptosporidial efficacy of the polyether anticoccidials alone and in combination with a new dihydroquinoline antioxidant, duokvin. The following efficacy percentages for the ionophores at the recommended level were established on the basis of oocyst output: lasalocid 45, monensin 37, semduramicin 29, narasin 23, and maduramicin and salinomycin 21. The efficacy of the ionophores, with the exception of lasalocid, could be increased to 36-88% by combination with duokvin. However, these combinations resulted in a significant weight gain reduction due to toxic interaction. Efficacy showed a strong negative correlation with body weight gain and bursa weight, suggesting an indirect mode of action against the parasite. It has been concluded that neither ionophorous anticoccidials nor their combinations with duokvin can be recommended for chemoprophylaxis against avian cryptosporidiosis.

Original languageHungarian
Pages (from-to)729-731
Number of pages3
JournalMagyar Allatorvosok Lapja
Volume51
Issue number12
Publication statusPublished - 1996

Fingerprint

Cryptosporidium baileyi
lasalocid
Cryptosporidium
coccidiostats
ionophores
Lasalocid
animal communication
Chickens
maduramicin
Communication
Ionophores
weight gain
narasin
chickens
salinomycin
cryptosporidiosis
chemoprevention
Weight Gain
monensin
oocysts

ASJC Scopus subject areas

  • veterinary(all)

Cite this

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title = "Az ionofor coccidiumellenes szerek potenci{\'a}l{\'a}sa duokvinnal - A Cryptosporidium baileyivel szembeni hat{\'e}konys{\'a}g h{\'a}zity{\'u}kban: M{\'a}sodk{\"o}zl{\'e}s",
abstract = "Three battery tests, employing 444 Arbor Acres chickens, were conducted to study the anticryptosporidial efficacy of the polyether anticoccidials alone and in combination with a new dihydroquinoline antioxidant, duokvin. The following efficacy percentages for the ionophores at the recommended level were established on the basis of oocyst output: lasalocid 45, monensin 37, semduramicin 29, narasin 23, and maduramicin and salinomycin 21. The efficacy of the ionophores, with the exception of lasalocid, could be increased to 36-88{\%} by combination with duokvin. However, these combinations resulted in a significant weight gain reduction due to toxic interaction. Efficacy showed a strong negative correlation with body weight gain and bursa weight, suggesting an indirect mode of action against the parasite. It has been concluded that neither ionophorous anticoccidials nor their combinations with duokvin can be recommended for chemoprophylaxis against avian cryptosporidiosis.",
author = "I. Varga and T. Sr{\'e}ter and B{\'e}k{\'e}si L{\'a}szl{\'o}",
year = "1996",
language = "Hungarian",
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pages = "729--731",
journal = "Magyar Allatorvosok Lapja",
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T1 - Az ionofor coccidiumellenes szerek potenciálása duokvinnal - A Cryptosporidium baileyivel szembeni hatékonyság házityúkban

T2 - Másodközlés

AU - Varga, I.

AU - Sréter, T.

AU - László, Békési

PY - 1996

Y1 - 1996

N2 - Three battery tests, employing 444 Arbor Acres chickens, were conducted to study the anticryptosporidial efficacy of the polyether anticoccidials alone and in combination with a new dihydroquinoline antioxidant, duokvin. The following efficacy percentages for the ionophores at the recommended level were established on the basis of oocyst output: lasalocid 45, monensin 37, semduramicin 29, narasin 23, and maduramicin and salinomycin 21. The efficacy of the ionophores, with the exception of lasalocid, could be increased to 36-88% by combination with duokvin. However, these combinations resulted in a significant weight gain reduction due to toxic interaction. Efficacy showed a strong negative correlation with body weight gain and bursa weight, suggesting an indirect mode of action against the parasite. It has been concluded that neither ionophorous anticoccidials nor their combinations with duokvin can be recommended for chemoprophylaxis against avian cryptosporidiosis.

AB - Three battery tests, employing 444 Arbor Acres chickens, were conducted to study the anticryptosporidial efficacy of the polyether anticoccidials alone and in combination with a new dihydroquinoline antioxidant, duokvin. The following efficacy percentages for the ionophores at the recommended level were established on the basis of oocyst output: lasalocid 45, monensin 37, semduramicin 29, narasin 23, and maduramicin and salinomycin 21. The efficacy of the ionophores, with the exception of lasalocid, could be increased to 36-88% by combination with duokvin. However, these combinations resulted in a significant weight gain reduction due to toxic interaction. Efficacy showed a strong negative correlation with body weight gain and bursa weight, suggesting an indirect mode of action against the parasite. It has been concluded that neither ionophorous anticoccidials nor their combinations with duokvin can be recommended for chemoprophylaxis against avian cryptosporidiosis.

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M3 - Article

VL - 51

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