Potential markers of the atherosclerotic process in high-risk children

Tamas Szamosi, Klara Mihai, Judit Peto, Anna Makary, J. Krámer

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Children whose parents had early coronary heart disease were investigated. In order to assess high-risk parameters serum total cholesterol (TC), total triglyceride (TT), high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol (LDLC), lipid peroxide (LP), prostacyclin (PGI2), thromboxane (TX) levels, and the distribution of the complement 3 (C3), protein phenotypes were measured. Compared to a group of control children, the offspring of high-risk subjects had increased LDLC, LP, TC, and TX levels, a higher incidence of fast-slow heterozygotes, and decreased HDLC and PGI2 levels. The measurement of serum PGI2, TX levels and the distribution of C3 protein phenotypes may give further information about the true risk of atherosclerosis.

Original languageEnglish
Pages (from-to)185-187
Number of pages3
JournalClinical Biochemistry
Volume24
Issue number2
DOIs
Publication statusPublished - 1991

Fingerprint

Epoprostenol
Thromboxanes
Complement C3
Lipid Peroxides
LDL Cholesterol
HDL Cholesterol
Complement System Proteins
Cholesterol
Phenotype
Heterozygote
Serum
Coronary Disease
Atherosclerosis
Triglycerides
Proteins
Parents
Control Groups
Incidence

Keywords

  • atherosclerosis risk factors
  • complement 3 phenotypes
  • lipid peroxides
  • prostacyclin
  • thromboxane

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Potential markers of the atherosclerotic process in high-risk children. / Szamosi, Tamas; Mihai, Klara; Peto, Judit; Makary, Anna; Krámer, J.

In: Clinical Biochemistry, Vol. 24, No. 2, 1991, p. 185-187.

Research output: Contribution to journalArticle

Szamosi, Tamas ; Mihai, Klara ; Peto, Judit ; Makary, Anna ; Krámer, J. / Potential markers of the atherosclerotic process in high-risk children. In: Clinical Biochemistry. 1991 ; Vol. 24, No. 2. pp. 185-187.
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