A Crohn-betegség posztoperatív kiújulása és a megelozés lehetoségei

Translated title of the contribution: Postoperative recurrence of Crohn's disease, and its prevention

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Crohn's disease is a chronic, progressive disabling condition ultimately leading to stricturing and/or penetrating complications. The need for surgery may be as high as 70% in patients with severe active disease or complications. However, relapse may develop in a significant proportion of the patients after surgery leading to frequent re-operations. Despite emerging data, postoperative prevention is still controversial. After careful evaluation of the individual risk a tailored therapy should be considered. In patients with small risk for relapse mesalazine or in selected cases no-treatment may be an option. In patients with a moderate-to-high risk azathioprine should be considered together with metronidazole in the three months. Follow-up ileocolonoscopy 6-12 months after the surgery is helpful in the determination of endoscopic severity and may assist in the optimization of the therapy. In most severe cases anti-TNF agents may be appropriate for postoperative prevention and therapy.

Original languageHungarian
Pages (from-to)870-877
Number of pages8
JournalOrvosi Hetilap
Volume151
Issue number21
DOIs
Publication statusPublished - May 1 2010

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Crohn Disease
Recurrence
Mesalamine
Metronidazole
Azathioprine
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A Crohn-betegség posztoperatív kiújulása és a megelozés lehetoségei. / Lakatos, L.; Lakatos, P.

In: Orvosi Hetilap, Vol. 151, No. 21, 01.05.2010, p. 870-877.

Research output: Contribution to journalArticle

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