Post-compressional studies of Vivacel® comprimates

K. Pintye-Hódi, P. Szabó-Révész, P. Kása, I. Langer, B. Selmeczi

Research output: Contribution to journalArticle

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Abstract

A computer-aided hardness tester (Chinoin Pharmaceutical Works, Budapest) was used to study the post-compressional breaking of Vivacel® 101 and 102 comprimates. The software permitted a qualitative evaluation of the breaking curves, and yielded the breaking work and the work necessary for deformation processes. The concept of the breaking factor was introduced; this can reveal differences between tablets even if they exhibit identical hardness.

Original languageEnglish
Pages (from-to)170-174
Number of pages5
JournalBollettino Chimico Farmaceutico
Volume135
Issue number3
Publication statusPublished - Mar 1 1996

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Keywords

  • breaking factor
  • breaking process
  • comprimates
  • microcrystalline cellulose
  • post-compressional study

ASJC Scopus subject areas

  • Molecular Medicine

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