Possible use of capsaicin in pain therapy

G. Jancsó, B. Lynn

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Capsaicin, the active ingredient in hot peppers, produces a long-lasting reduction of nociceptive reactions in rodents through a selective toxic action of afferent C-fibres. Immediate effects on C-fibre conduction are also found in other mammalian species and a reduction in nociceptive responses from human skin occurs following topical application. Direct application to nerve trunks may be expected to produce a useful degree of regional analgesia in man. Since this effect would occur without any anaesthesia or paralysis, it appears worth investigating as a treatment for pain of peripheral origin in man.

Original languageEnglish
Pages (from-to)123-126
Number of pages4
JournalClinical Journal of Pain
Volume3
Issue number3
Publication statusPublished - 1987

Fingerprint

Unmyelinated Nerve Fibers
Capsaicin
Toxic Actions
Pain
Capsicum
Paralysis
Analgesia
Rodentia
Anesthesia
Skin
Therapeutics

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Clinical Neurology

Cite this

Possible use of capsaicin in pain therapy. / Jancsó, G.; Lynn, B.

In: Clinical Journal of Pain, Vol. 3, No. 3, 1987, p. 123-126.

Research output: Contribution to journalArticle

Jancsó, G & Lynn, B 1987, 'Possible use of capsaicin in pain therapy', Clinical Journal of Pain, vol. 3, no. 3, pp. 123-126.
Jancsó, G. ; Lynn, B. / Possible use of capsaicin in pain therapy. In: Clinical Journal of Pain. 1987 ; Vol. 3, No. 3. pp. 123-126.
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