Possible use of capsaicin in pain therapy

G. Jancso, B. Lynn

Research output: Contribution to journalArticle

27 Citations (Scopus)


Capsaicin, the active ingredient in hot peppers, produces a long-lasting reduction of nociceptive reactions in rodents through a selective toxic action of afferent C-fibres. Immediate effects on C-fibre conduction are also found in other mammalian species and a reduction in nociceptive responses from human skin occurs following topical application. Direct application to nerve trunks may be expected to produce a useful degree of regional analgesia in man. Since this effect would occur without any anaesthesia or paralysis, it appears worth investigating as a treatment for pain of peripheral origin in man.

Original languageEnglish
Pages (from-to)123-126
Number of pages4
JournalClinical Journal of Pain
Issue number3
Publication statusPublished - Jan 1 1987

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine

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