Possible role of serotonin in the monoamines induced inhibition of the stress mechanism in the rat

I. Vermes, G. Dull, G. Telegdy, K. Lissak

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Intraventricularly administered 5 μg dopamine, 5 μg norepinephrine or 165 μg melatonin inhibited the activation by surgical stress of the pituitary adrenal system, and increased the hypothalamic serotonin content. p Chlorophenylalanine (300 μg/kg b.w.) prevented the inhibition by monoamines of the stress by lowering the serotonin content in the hypothalamus. According to the results, the inhibition of stress by monoamines is mediated via increased hypothalamic serotonin content.

Original languageEnglish
Pages (from-to)219-223
Number of pages5
JournalActa physiologica Academiae Scientiarum Hungaricae
Volume42
Issue number3
Publication statusPublished - Dec 1 1972

    Fingerprint

ASJC Scopus subject areas

  • Physiology

Cite this