Possible role of prostaglandins in cardiac electrogenesis

K. Kelemen, V. Kecskemeti, J. Knoll

Research output: Contribution to journalArticle

Abstract

PGE compounds increase the rapid sodium inward current through the cardiac cell membrane without influencing its slow component. Considering the effects of epinephrine, cellulin A and prostaglandins on cardiac transmembrane potentials, transmembrane currents and on the exchange diffusion of sodium across the cardiac cell membrane, a model has been proposed to explain the sodium permeability changes in the heart cells indicating the possible role of prostaglandins in these processes.

Original languageEnglish
Pages (from-to)177-186
Number of pages10
JournalPolish journal of pharmacology and pharmacy
Volume26
Issue number1-2
Publication statusPublished - Jan 1 1974

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ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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