A humán szöveti (felnótt) óssejtek kutatása és klinikai alkalmazási lehetóségei.

Translated title of the contribution: Possibilities of investigation and clinical application of adult human stem cells

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Multipotent adult tissue stem cells have high plasticity and transdifferentiation ability. The stem cell therapy can be the solution of curing many severe diseases such as osteogenesis imperfecta, hepatic failure, heart muscle damage after myocardial infarction, I-type diabetes, variety of central nervous system disorders such as brain injury, stroke, Parkinson's disease and other neurodegenerative disorders. Isolation of certain types of stem cells is solved nowadays, but low frequency of these cells and lack of special identification markers make their isolation and search more difficult. The more and more developed in vitro cell culture technologies, the widespread macromolecule amplification and examination techniques of molecular biology and the gene technology tools for genetic modification of stem (and other) cells contribute to research and therapeutic applications of stem cells. Transfer of new genetic material to stem cells and expression of the gene product in daughter cells--because missing or damaged genes can be replaced--is an exiting approach of the treatment of congenital (enzyme deficiencies) and acquired human diseases (cancers).

Original languageHungarian
Pages (from-to)2263-2270
Number of pages8
JournalOrvosi Hetilap
Volume144
Issue number46
Publication statusPublished - Nov 16 2003

Fingerprint

Adult Stem Cells
Stem Cells
Multipotent Stem Cells
Genes
Therapeutic Human Experimentation
Technology
Osteogenesis Imperfecta
Central Nervous System Diseases
Liver Failure
Cell- and Tissue-Based Therapy
Neurodegenerative Diseases
Brain Injuries
Parkinson Disease
Molecular Biology
Myocardium
Cell Culture Techniques
Stroke
Myocardial Infarction
Gene Expression
Enzymes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A humán szöveti (felnótt) óssejtek kutatása és klinikai alkalmazási lehetóségei. / Galamb, O.; Molnár, B.; Sípos, F.; Tulassay, Z.

In: Orvosi Hetilap, Vol. 144, No. 46, 16.11.2003, p. 2263-2270.

Research output: Contribution to journalArticle

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