Positive predictive value of prenatal ultrasonography confirmed by post-mortem investigations

József Gábor Joó, Éva Csatlós, Ákos Csaba, János Rigó

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5 Citations (Scopus)

Abstract

Objective: To analyse the positive predictive value of ultrasonography based on the results of post-mortem investigations in respect of the most common malformations. Study design: We processed the details of 683 cases affecting the nervous, cardiovascular, urinary and skeletal systems, and the abdominal/thoracic walls. Results: In four of the investigated groups of malformations, the proportion of sonographic diagnoses completely coinciding with the post mortem results was found to be approximately 70%, but it was found to be much lower (32%) in urinary malformations. The cumulative proportion of coinciding sonographic and post mortem diagnoses was 63%, while completely incorrect ultrasonographic diagnoses amounted to 17%. Conclusions: Sonography is an essential method for the diagnosis of the majority of fetal malformations, but post-mortem examinations yield an indispensable quality control as well as additional information to ultrasound examinations.

Original languageEnglish
Pages (from-to)149-152
Number of pages4
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Volume156
Issue number2
DOIs
Publication statusPublished - Jun 2011

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Keywords

  • Autopsy
  • Fetal malformations
  • Fetopathological investigation
  • Positive predictive value of sonography
  • Post mortem examination
  • Ultrasonography

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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