Population-based case-control study of allergic rhinitis during pregnancy for birth outcomes

Ákos Somoskövi; Zoltán Bártfai; Lilla Tamási; Judit Kocsis; Erzsébet Puhó; Andrew E. Czeizel

doi:10.1016/j.ejogrb.2005.11.035

Population-based case-control study of allergic rhinitis during pregnancy for birth outcomes

Ákos Somoskövi, Zoltán Bártfai, Lilla Tamási, Judit Kocsis, Erzsébet Puhó, Andrew E. Czeizel

Research output: Contribution to journal › Article

15 Citations (Scopus)

Abstract

Objective: Allergic rhinitis is frequent in women of childbearing age including pregnancy. The present study aimed to estimate the effect of maternal allergic rhinitis on birth outcomes, in particular congenital abnormalities, preterm birth and low birthweight newborns. Study design: Analysis of the population-based data of the Hungarian Case-Control Surveillance of Congenital Abnormalities between 1980 and 1996. Results: The evaluation of data did not reveal any teratogenic potential of allergic rhinitis and indeed a lower prevalence of total congenital abnormalities was found. In addition, a protective effect could be observed for preterm birth due to longer gestational age (adjusted t = 2.97, p = 0.003). Conclusion: Allergic rhinitis is not risk factor for pregnant women.

Original language	English
Pages (from-to)	21-27
Number of pages	7
Journal	European Journal of Obstetrics and Gynecology and Reproductive Biology
Volume	131
Issue number	1
DOIs	https://doi.org/10.1016/j.ejogrb.2005.11.035
Publication status	Published - Mar 2007

Keywords

Allergic rhinitis
Congenital abnormalities
Pharmacological treatment
Pregnancy outcome
Preterm birth

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynaecology

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Somoskövi, Á., Bártfai, Z., Tamási, L., Kocsis, J., Puhó, E., & Czeizel, A. E. (2007). Population-based case-control study of allergic rhinitis during pregnancy for birth outcomes. European Journal of Obstetrics and Gynecology and Reproductive Biology, 131(1), 21-27. https://doi.org/10.1016/j.ejogrb.2005.11.035

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abstract = "Objective: Allergic rhinitis is frequent in women of childbearing age including pregnancy. The present study aimed to estimate the effect of maternal allergic rhinitis on birth outcomes, in particular congenital abnormalities, preterm birth and low birthweight newborns. Study design: Analysis of the population-based data of the Hungarian Case-Control Surveillance of Congenital Abnormalities between 1980 and 1996. Results: The evaluation of data did not reveal any teratogenic potential of allergic rhinitis and indeed a lower prevalence of total congenital abnormalities was found. In addition, a protective effect could be observed for preterm birth due to longer gestational age (adjusted t = 2.97, p = 0.003). Conclusion: Allergic rhinitis is not risk factor for pregnant women.",

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AU - Somoskövi, Ákos

AU - Bártfai, Zoltán

AU - Tamási, Lilla

AU - Kocsis, Judit

AU - Puhó, Erzsébet

AU - Czeizel, Andrew E.

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AB - Objective: Allergic rhinitis is frequent in women of childbearing age including pregnancy. The present study aimed to estimate the effect of maternal allergic rhinitis on birth outcomes, in particular congenital abnormalities, preterm birth and low birthweight newborns. Study design: Analysis of the population-based data of the Hungarian Case-Control Surveillance of Congenital Abnormalities between 1980 and 1996. Results: The evaluation of data did not reveal any teratogenic potential of allergic rhinitis and indeed a lower prevalence of total congenital abnormalities was found. In addition, a protective effect could be observed for preterm birth due to longer gestational age (adjusted t = 2.97, p = 0.003). Conclusion: Allergic rhinitis is not risk factor for pregnant women.

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