The first histologically and clinically documented case of pneumoconiosis caused by prolonged polyvinyl chloride (PVC) inhalation was described in 1970. A series of human epidemiological as well as some experimental studies confirmed the existence of PVC pneumoconiosis. Pyrolytic products of PVC, of vinyl chloride and of plasticisers and stabilisers may irritate the respiratory organs, causing fibrosis, asthma, bronchitis and even cancer of the lung. Work ers employed in PVC plants are at high risk with respect to PVC-induced lung disease.
- Polyvinyl chloride
- Vinyl chloride monomer
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health