Polyurethane Microstructures--a Good or Bad in vitro Partner for the Isoflavone Genistein?

Corina Danciu, Florin Borcan, Codruta Soica, I. Zupkó, Erzsébet Csányi, Rita Ambrus, Delia Muntean, Camelia Sass, Diana Antal, Claudia Toma, Cristina Dehelean

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In recent years polyurethane microstructures (PM) have gained increasing attention in the pharmaceutical field due to the importance of their practical application. Since finding that such a formulation with genistein could improve its applications, we have conducted a preliminary study regarding the in vitro antiproliferative (MCF7, MDA-MB-231 and T47D) and antimicrobial (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enteritidis (D), Bacillus subtilis, B. cereus, and Candida albicans) activity in order to test whether polyurethane micro structuresre present a good option for further modulation of genistein's bioavailability. It was concluded that the polyurethane micro structures are a bad in vitro partner for the isoflavone genistein.

Original languageEnglish
Pages (from-to)951-954
Number of pages4
JournalNatural Product Communications
Volume10
Issue number6
Publication statusPublished - Jun 1 2015

Fingerprint

polyurethanes
Isoflavones
Polyurethanes
Genistein
genistein
isoflavones
microstructure
Salmonella enteritidis
Salmonella Enteritidis
Bacillus cereus
Bacillus subtilis
Candida albicans
Pseudomonas aeruginosa
in vitro studies
Biological Availability
Staphylococcus aureus
bioavailability
anti-infective agents
Escherichia coli
drugs

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

Cite this

Danciu, C., Borcan, F., Soica, C., Zupkó, I., Csányi, E., Ambrus, R., ... Dehelean, C. (2015). Polyurethane Microstructures--a Good or Bad in vitro Partner for the Isoflavone Genistein? Natural Product Communications, 10(6), 951-954.

Polyurethane Microstructures--a Good or Bad in vitro Partner for the Isoflavone Genistein? / Danciu, Corina; Borcan, Florin; Soica, Codruta; Zupkó, I.; Csányi, Erzsébet; Ambrus, Rita; Muntean, Delia; Sass, Camelia; Antal, Diana; Toma, Claudia; Dehelean, Cristina.

In: Natural Product Communications, Vol. 10, No. 6, 01.06.2015, p. 951-954.

Research output: Contribution to journalArticle

Danciu, C, Borcan, F, Soica, C, Zupkó, I, Csányi, E, Ambrus, R, Muntean, D, Sass, C, Antal, D, Toma, C & Dehelean, C 2015, 'Polyurethane Microstructures--a Good or Bad in vitro Partner for the Isoflavone Genistein?', Natural Product Communications, vol. 10, no. 6, pp. 951-954.
Danciu, Corina ; Borcan, Florin ; Soica, Codruta ; Zupkó, I. ; Csányi, Erzsébet ; Ambrus, Rita ; Muntean, Delia ; Sass, Camelia ; Antal, Diana ; Toma, Claudia ; Dehelean, Cristina. / Polyurethane Microstructures--a Good or Bad in vitro Partner for the Isoflavone Genistein?. In: Natural Product Communications. 2015 ; Vol. 10, No. 6. pp. 951-954.
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