Polymerization dependence of the entropy of homo-oligomer peptides

B. Viskolcz, I. Csizmadia, Svend J Knak Jensen, A. Perczel

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Statistical mechanical principles are used to derive the approximate relationship of c1 + c2ln(n) + c3n for the entropy of homo-oligo peptides with n residues, where c1, c 2 and c3 are constants for a specific polypeptide chain. The relationship is tested in the range 1 ≤ n ≤ 34 against entropy data derived from electron structure calculations completed both at the Hartree-Fock and the density functional levels of theory. We have found that the above equation provides a good representation of the entropy of oligoglycine and oligoalanine model systems when they fold from an extended-like to a helical conformation.

Original languageEnglish
Pages (from-to)30-32
Number of pages3
JournalChemical Physics Letters
Volume501
Issue number1-3
DOIs
Publication statusPublished - Dec 6 2010

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oligomers
Oligomers
peptides
Entropy
polymerization
Polymerization
entropy
Peptides
polypeptides
Conformations
Electrons
electrons

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Physics and Astronomy(all)

Cite this

Polymerization dependence of the entropy of homo-oligomer peptides. / Viskolcz, B.; Csizmadia, I.; Jensen, Svend J Knak; Perczel, A.

In: Chemical Physics Letters, Vol. 501, No. 1-3, 06.12.2010, p. 30-32.

Research output: Contribution to journalArticle

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