Poly(amino acid)-Based Gel Fibers with pH Responsivity by Coaxial Reactive Electrospinning

Kristof Molnar, Angela Jedlovszky-Hajdu, M. Zrínyi, Shaohua Jiang, Seema Agarwal

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Electrospinning is a well-known technique for the preparation of scaffolds for biomedical applications. In this work, a continuous electrospinning method for gel fiber preparation is presented without a spinning window. As proof of concept, the preparation of poly(aspartic acid)-based hydrogel fibers and their properties are described by using poly(succinimide) as shell polymer and 2,2,4(2,4,4)-trimethyl-1,6-hexanediamine as cross-linker in the core of the nozzle. Cross-linking takes place as the two solutions get in contact at the tip of the nozzle. The impact of solution concentrations and feeding rates on fiber morphology, proof of the presence of cross-links as well as pH sensitivity after the transformation of the poly(succinimide)-based material to poly(aspartic acid) is presented. (Figure presented.).

Original languageEnglish
Article number1700147
JournalMacromolecular Rapid Communications
Volume38
Issue number14
DOIs
Publication statusPublished - Jul 1 2017

Keywords

  • coaxial spinning
  • gel fibers
  • pH sensitivity
  • poly(amino acid)
  • reactive electrospinning

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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