Pole reversals and hypothalamic self-stimulation: Ascending spread of rewarding excitation

I. Szabó, Éva Nád, Csilla Szabó

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Direction of the spread of rewarding impulses has been studied by analysis the changes in the efficiency of monophasic square wave pulses established by reversing the position of cathode (which is the active pole for self-stimulation) and anode (under which blockade of neural conduction may occur) for the same two wires of such bipolar electrodes whose two poles were aligned sagittally in lateral hypothalamus of rats. Lower bipolar self-stimulation thresholds were observed to belong to the anterior cathodal and posterior anodal pole positions and the same current level was found to maintain higher rate of bar pressing in this case than when stimulations with reversed cathodal-anodal pole positions were applied. This finding suggests that rewarding excitation starts to spread in anterior direction from the active pole of lateral hypothalamic self-stimulation electrodes.

Original languageEnglish
Pages (from-to)147-150
Number of pages4
JournalPhysiology and Behavior
Volume9
Issue number2
DOIs
Publication statusPublished - 1972

Fingerprint

Self Stimulation
Electrodes
Lateral Hypothalamic Area
Neural Conduction
Direction compound

Keywords

  • Anatomy of reward
  • Anodal block
  • Lateral hypothalamus
  • Medial forebrain bundle
  • Pole reversal
  • Reinforement
  • Self-stimulation

ASJC Scopus subject areas

  • Physiology (medical)
  • Behavioral Neuroscience

Cite this

Pole reversals and hypothalamic self-stimulation : Ascending spread of rewarding excitation. / Szabó, I.; Nád, Éva; Szabó, Csilla.

In: Physiology and Behavior, Vol. 9, No. 2, 1972, p. 147-150.

Research output: Contribution to journalArticle

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