Polarization colours of collagen fibres: A sign of collagen production activity in fibrotic processes

M. Szendrői, G. Vajta, L. Kovacs

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

The maturation process of collagen fibres was investigated by the picro-sirius red/polarization light technique in experimental wound healing, in allyl-alcohol induced subacute and chronic liver fibrosis and in human biopsy material. Evidence was obtained that collagen fibres undergo a rapid maturation in fibrotic processes; the intensity of their birefringence increases and, at the same time, their polarization colour changes. Newly formed collagen fibres appear on the 4-6 μm thick sections in green polarization colour. Later, in a more mature stage, they became yellow, orange or red under crossed polaroids. The findings suggest that the simple picro-sirius red/polarizing light technique may be useful to form an opinion about the activity of the fibrotic process.

Original languageEnglish
Pages (from-to)47-55
Number of pages9
JournalActa Morphologica Hungarica
Volume32
Issue number1
Publication statusPublished - 1984

Fingerprint

Collagen
Color
Birefringence
Light
Liver Cirrhosis
Wound Healing
Biopsy
allyl alcohol

ASJC Scopus subject areas

  • Anatomy

Cite this

Polarization colours of collagen fibres : A sign of collagen production activity in fibrotic processes. / Szendrői, M.; Vajta, G.; Kovacs, L.

In: Acta Morphologica Hungarica, Vol. 32, No. 1, 1984, p. 47-55.

Research output: Contribution to journalArticle

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