Background: Anticoagulant rodenticides are most commonly used for extermination of rodents in Hungary, so this type of poisoning often occurs. Objectives: The aim of this survey was to describe the experiences of toxicological studies of animal carcasses and other types of test samples received in the laboratory from 2010 to 2016 with suspicion poisoning with anticoagulant rodenticides. Material and Methods: During the period under review, 112 animal subjects were examined. In 32 cases, 4 types of 4-hydroxycoumarin derivatives (warfarin, coumatetralyl, bromadiolone, brodifacoum) were detected by HPLC, and in 6 cases, the chlorophacinone of the indandlone group was tested with GC-MS. In addition to the examination of animal carcasses, 51 baits were analysed for the presence of 4-hydroxycoumarin derivatives. Result and Discussion: Traces of four different 4-hydroxycoumarin derivatives (bromadiolone, brodifacoum, warfarin, coumatetralyl) and one indandlone derivative (chlorophacinone) were found in the organ of 38 carcasses (11 dogs, 3 cats, 1 goat, 1 Wolf, 1 orangutan, 9 rabbits, 6 deer, 1 otter, 2 foxes, 1 hyena, 1 buzzard, 1 African sacred ibis). Mild to severe coagulation problems were observed in the above cases indicative of anti coagulant rodenticide poisoning. Given the circumstances, these deaths were predominantly malicious poisoning, although some of the cases may have been accidental. Among the poisonings 16 of them were caused by bromadialone, and 13 of themby brodifacoum, which is 76% of the cases. Six different 4-hydroxycoumarin derivatives were detected ( bromadialone, brodifocoum, difenacoum, flocoumafen, warfarin, coumatetralyl) in 41 baits of 51. Since the use of anticoagulant rodenticides is required in the defence against rodents, poisoning of this type should also be expected in the future.
|Translated title of the contribution||Poisonings caused by anticoagulant rodenticides between 2010 and 2016|
|Number of pages||10|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Dec 1 2017|
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