Plexiform fibrohistiocytic tumour with novel phenotypic features

V. THOMÁZY, A. NAGY, I. GAL, Z. NEMES

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Abstract

Plexiform fibrohistiocytic tumour is a recently described type of fibrohistiocytic tumour, the differentiation pattern of which is poorly understood. A case representing the predominantly fibrohistiocytic type of the tumour is reported. Immunohistochemical analysis supports the histiocytic origin of this entity. The expression of EBM/11 and tissue transglutaminase both in fibroblast‐like and histiocyte‐like cells indicate that a single cell line produces the dual morphological features. It is proposed that a non‐phagocytic epithelioid pattern of histiocytic differentiation characterizes this tumour.

Original languageEnglish
Pages (from-to)165-169
Number of pages5
JournalHistopathology
Volume25
Issue number2
DOIs
Publication statusPublished - Aug 1994

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Keywords

  • histiocytic differentiation
  • plexiform histiocytic tumour. EBM/11
  • tissue transglutaminase

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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