Enantioselective hydroformylation of styrene was carried out in the presence of platinum-containing catalysts. Tin(II) fluoride was used as cocatalyst, giving a catalytic system of unusually high stability. When the optically active diphosphine 2,4-bis(diphenylphosphino)pentane (BDPP) was used the absolute configuration of the 2-phenylpropanal formed varied with the temperature used. In dichloromethane the enantiomeric excess depends strongly on the temperature used. Although the addition of 2-diphenylphosphino-pyridine to the catalytic system strongly reduces the catalytic activity, the BDPP-2-diphenylphosphino-pyridine "mixed-phosphine system" gave 86.7% e.e.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry
- Materials Chemistry