Platelet MAO activity and the dexamethasone suppression test in bipolar depression

G. Bagdy, Z. Rihmer, E. Frecska, E. Szádóczky, M. Arató

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The correlation between postdexamethasone cortisol levels after the dexamethasone suppression test (DST) and platelet monoamine oxidase (MAO) activity was studied in 31 depressed female inpatients with Research Diagnostic Criteria primary, endogenous, bipolar depression (12 bipolar I and 19 bipolar II). Out of the 31 patients, 25 showed abnormal DST results. Platelet MAO activity did not differ significantly from the matched control group. There was a trend that patients with higher MAO activity had lower postdexamethasone cortisol levels, but it was significant only for the 0800 hr cortisol levels.

Original languageEnglish
Pages (from-to)117-120
Number of pages4
JournalPsychoneuroendocrinology
Volume11
Issue number1
DOIs
Publication statusPublished - 1986

Keywords

  • DST
  • MAO
  • bipolar depression

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Endocrine and Autonomic Systems
  • Psychiatry and Mental health
  • Biological Psychiatry

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