Platelet aggregation, blood viscosity and serum lipids in hypertensive and obese children

I. Haszon, Ferenc Papp, József Kovács, Melinda Bors, I. Németh, C. Bereczki, S. Túri

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A group of 35 patients (median age 15.5 years, range 8-17 years) with juvenile essential hypertension, 15 with body mass index (BMI kg/m2) <25 and 20 with BMI > 25, as well as 35 age and sex matched controls (BMI 25 n=15) were investigated to study the role of hypertension and obesity, separately and in combination, on in vitro platelet aggregation, blood and plasma viscosity, plasma lipid concentrations and lipid peroxidation as well as nitric oxide (NO) production. Obese children (hypertensive and controls) had significantly higher concentrations of total cholesterol and triglycerides. The levels of high density lipoprotein (HDL)-cholesterol were lower in obese hypertensive children than their non-obese counterparts. There was a significant increase in platelet aggregation and a decrease in NO levels in hypertensive patients (obese and non-obese) reflecting a significant negative correlation (r=-0.553 and -0.530, n=35; P

Original languageEnglish
Pages (from-to)385-390
Number of pages6
JournalEuropean Journal of Pediatrics
Volume162
Issue number6
Publication statusPublished - Jun 1 2003

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Blood Viscosity
Platelet Aggregation
Nitric Oxide
Lipids
Serum
HDL Cholesterol
Lipid Peroxidation
Triglycerides
Body Mass Index
Obesity
Cholesterol
Hypertension
Essential Hypertension
In Vitro Techniques

Keywords

  • Hyperlipidaemia
  • Hypertension
  • Obesity
  • Platelet aggregation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Platelet aggregation, blood viscosity and serum lipids in hypertensive and obese children. / Haszon, I.; Papp, Ferenc; Kovács, József; Bors, Melinda; Németh, I.; Bereczki, C.; Túri, S.

In: European Journal of Pediatrics, Vol. 162, No. 6, 01.06.2003, p. 385-390.

Research output: Contribution to journalArticle

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AU - Túri, S.

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