Platelet activating factor, the trigger of haemostatic alterations in rat anaphylaxis

L. Fesus, B. Csaba, L. Muszbek

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Platelet activating factor (PAF) generated by an IgE mediated reaction in the peritoneal cavity of rats was partially purified by adsorption to diatomaceous earth. It aggregated rat platelets and, as a consequence, activated Hageman factor in in vitro, as well as in in vitro, conditions. The heamostatic alterations induced by PAF showed similarity to those observed in the early phase of rat anaphylaxis.

Original languageEnglish
Pages (from-to)512-515
Number of pages4
JournalClinical and Experimental Immunology
Volume27
Issue number3
Publication statusPublished - Jan 1 1977

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Fingerprint Dive into the research topics of 'Platelet activating factor, the trigger of haemostatic alterations in rat anaphylaxis'. Together they form a unique fingerprint.

  • Cite this