Plasma prolactin levels in full-term newborn infants with idiopathic edema: Response to furosemide

T. Ertl, E. Sulyok, J. Bodis, I. F. Csaba

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In an attempt to explore the possible role of prolactin (PRL) in the control of neonatal electrolyte homeostasis, this study has been carried out to compare plasma electrolyte concentrations, urine volume and urinary electrolyte excretion as well as plasma PRL levels in healthy full-term neonates with idiopathic edema prior to and after furosemide treatment. No differences in plasma sodium and potassium were demonstrated, edematous neonates, however, had less urine volume and sodium excretion than neonates without edema. Plasma PRL proved to be significantly higher in the edematous group (11.0 ± 1.9 vs. 4.2 ± 3.1 U/l, p <0.01) but it remained unaltered by furosemide challenge (8.5 ± 1.5 U/l) in spite of the marked elevation of urine flow and sodium excretion. It is concluded that PRL may be involved in the control of the volume and composition of the body fluids in the neonate but further studies are needed to define the effect of changes in body composition on the neonatal PRL secretion.

Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalBiology of the Neonate
Volume49
Issue number1
Publication statusPublished - 1986

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Furosemide
Prolactin
Edema
Newborn Infant
Electrolytes
Sodium
Urine
Body Fluids
Body Composition
Potassium
Homeostasis

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

Cite this

Plasma prolactin levels in full-term newborn infants with idiopathic edema : Response to furosemide. / Ertl, T.; Sulyok, E.; Bodis, J.; Csaba, I. F.

In: Biology of the Neonate, Vol. 49, No. 1, 1986, p. 15-20.

Research output: Contribution to journalArticle

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