Plasma lipids, phospholipid fatty acids and indices of glycaemia in 10- year-old children born as small-for-gestational-age or preterm infants

T. Decsi, E. Erhardt, A. Márkus, I. Burns, D. Molnár

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Low birthweight has been epidemiologically associated with unfavourable plasma lipid profiles and enhanced risk of cardiovascular morbidity in adulthood. Plasma lipids, lipoprotein cholesterols, apolipoproteins, fatty acid composition of plasma phospholipids and basic indices of glycaemia were investigated in 10-y-old children born with similarly low birthweights as small-forgestational-age (SGA; n = 16) or preterm infants (n = 16). Plasma total cholesterol (4,32 ± 0.57 vs 4.60 ± 0.52, mmol 1-1, mean ± SD, SGA vs preterm subjects), low-density lipoprotein cholesterol (2.54 ± 0.51 vs 2. 65 ± 0.51) and high-density lipoprotein cholesterol (1.61 ± 0.25 vs 1.76 ± 0.18) concentrations did not differ between the 2 groups. There was no difference in plasma triacylglycerol, apolipoprotein A-I and B, insulin and glucose concentrations or phospholipid fatty acid values. There was no correlation between indices of lipid and carbohydrate metabolism. In conclusion, plasma lipid profiles and basic indices of glycaemia are not different in 10-y-old children born with similarly low birthweights as SGA or preterm infants.

Original languageEnglish
Pages (from-to)500-504
Number of pages5
JournalActa Paediatrica, International Journal of Paediatrics
Volume88
Issue number5
DOIs
Publication statusPublished - 1999

Fingerprint

Small for Gestational Age Infant
Premature Infants
Phospholipids
Fatty Acids
Lipids
Apolipoproteins
Apolipoprotein A-I
Carbohydrate Metabolism
Apolipoproteins B
Lipid Metabolism
LDL Cholesterol
HDL Cholesterol
Triglycerides
Cholesterol
Morbidity
Glucose

Keywords

  • 10-y-old children
  • Apolipoprotein
  • Cholesterol
  • Insulin
  • Lipoprotein cholesterol
  • Low birthweight
  • Phospholipid fatty acid

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

@article{891fc27f504d442c9ebd1a8b210dbb94,
title = "Plasma lipids, phospholipid fatty acids and indices of glycaemia in 10- year-old children born as small-for-gestational-age or preterm infants",
abstract = "Low birthweight has been epidemiologically associated with unfavourable plasma lipid profiles and enhanced risk of cardiovascular morbidity in adulthood. Plasma lipids, lipoprotein cholesterols, apolipoproteins, fatty acid composition of plasma phospholipids and basic indices of glycaemia were investigated in 10-y-old children born with similarly low birthweights as small-forgestational-age (SGA; n = 16) or preterm infants (n = 16). Plasma total cholesterol (4,32 ± 0.57 vs 4.60 ± 0.52, mmol 1-1, mean ± SD, SGA vs preterm subjects), low-density lipoprotein cholesterol (2.54 ± 0.51 vs 2. 65 ± 0.51) and high-density lipoprotein cholesterol (1.61 ± 0.25 vs 1.76 ± 0.18) concentrations did not differ between the 2 groups. There was no difference in plasma triacylglycerol, apolipoprotein A-I and B, insulin and glucose concentrations or phospholipid fatty acid values. There was no correlation between indices of lipid and carbohydrate metabolism. In conclusion, plasma lipid profiles and basic indices of glycaemia are not different in 10-y-old children born with similarly low birthweights as SGA or preterm infants.",
keywords = "10-y-old children, Apolipoprotein, Cholesterol, Insulin, Lipoprotein cholesterol, Low birthweight, Phospholipid fatty acid",
author = "T. Decsi and E. Erhardt and A. M{\'a}rkus and I. Burns and D. Moln{\'a}r",
year = "1999",
doi = "10.1080/08035259950169495",
language = "English",
volume = "88",
pages = "500--504",
journal = "Acta Paediatrica, International Journal of Paediatrics",
issn = "0803-5253",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Plasma lipids, phospholipid fatty acids and indices of glycaemia in 10- year-old children born as small-for-gestational-age or preterm infants

AU - Decsi, T.

AU - Erhardt, E.

AU - Márkus, A.

AU - Burns, I.

AU - Molnár, D.

PY - 1999

Y1 - 1999

N2 - Low birthweight has been epidemiologically associated with unfavourable plasma lipid profiles and enhanced risk of cardiovascular morbidity in adulthood. Plasma lipids, lipoprotein cholesterols, apolipoproteins, fatty acid composition of plasma phospholipids and basic indices of glycaemia were investigated in 10-y-old children born with similarly low birthweights as small-forgestational-age (SGA; n = 16) or preterm infants (n = 16). Plasma total cholesterol (4,32 ± 0.57 vs 4.60 ± 0.52, mmol 1-1, mean ± SD, SGA vs preterm subjects), low-density lipoprotein cholesterol (2.54 ± 0.51 vs 2. 65 ± 0.51) and high-density lipoprotein cholesterol (1.61 ± 0.25 vs 1.76 ± 0.18) concentrations did not differ between the 2 groups. There was no difference in plasma triacylglycerol, apolipoprotein A-I and B, insulin and glucose concentrations or phospholipid fatty acid values. There was no correlation between indices of lipid and carbohydrate metabolism. In conclusion, plasma lipid profiles and basic indices of glycaemia are not different in 10-y-old children born with similarly low birthweights as SGA or preterm infants.

AB - Low birthweight has been epidemiologically associated with unfavourable plasma lipid profiles and enhanced risk of cardiovascular morbidity in adulthood. Plasma lipids, lipoprotein cholesterols, apolipoproteins, fatty acid composition of plasma phospholipids and basic indices of glycaemia were investigated in 10-y-old children born with similarly low birthweights as small-forgestational-age (SGA; n = 16) or preterm infants (n = 16). Plasma total cholesterol (4,32 ± 0.57 vs 4.60 ± 0.52, mmol 1-1, mean ± SD, SGA vs preterm subjects), low-density lipoprotein cholesterol (2.54 ± 0.51 vs 2. 65 ± 0.51) and high-density lipoprotein cholesterol (1.61 ± 0.25 vs 1.76 ± 0.18) concentrations did not differ between the 2 groups. There was no difference in plasma triacylglycerol, apolipoprotein A-I and B, insulin and glucose concentrations or phospholipid fatty acid values. There was no correlation between indices of lipid and carbohydrate metabolism. In conclusion, plasma lipid profiles and basic indices of glycaemia are not different in 10-y-old children born with similarly low birthweights as SGA or preterm infants.

KW - 10-y-old children

KW - Apolipoprotein

KW - Cholesterol

KW - Insulin

KW - Lipoprotein cholesterol

KW - Low birthweight

KW - Phospholipid fatty acid

UR - http://www.scopus.com/inward/record.url?scp=0032995328&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032995328&partnerID=8YFLogxK

U2 - 10.1080/08035259950169495

DO - 10.1080/08035259950169495

M3 - Article

C2 - 10426171

AN - SCOPUS:0032995328

VL - 88

SP - 500

EP - 504

JO - Acta Paediatrica, International Journal of Paediatrics

JF - Acta Paediatrica, International Journal of Paediatrics

SN - 0803-5253

IS - 5

ER -