A vérplazma elektrolitjai myeloma multiplexben.

Translated title of the contribution: Plasma electrolytes in multiple myeloma

A. Miseta, M. Kellermayer, F. Liszt, A. Ludány, T. Magyarlaki, K. Sipos, G. Berkó, M. Tókés-Fúzesi

Research output: Contribution to journalArticle

Abstract

The plasma cell myeloma (multiple myeloma, myelomatosis) is a progressive disease, characterized by bone marrow plasmacytomas and the presence of monoclonal antibodies (IgG, IgA, IgD, IgE), or free kappa or lambda immunoglobulin side chains. The monoclonal antibodies or Bence-Jones protein may precipitate in the tubuli and impair kidney function. In addition, the plasma protein concentration may increase at the expense of plasma water level causing unrealistically low electrolyte levels. Since the isoelectric points of immunoglobulins are higher than those of most other plasma proteins, the net charge of plasma proteins may change causing new electrolyte balance. In addition, some monoclonal antibodies are more hydrated than others, and their high concentration may cause not only increased plasma viscosity but further electrolyte imbalance. In the present work the relationship between plasma protein and electrolyte levels is studied in samples of 100 multiple myeloma patients.

Translated title of the contributionPlasma electrolytes in multiple myeloma
Original languageHungarian
Pages (from-to)1449-1453
Number of pages5
JournalOrvosi hetilap
Volume142
Issue number27
Publication statusPublished - Jul 8 2001

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Miseta, A., Kellermayer, M., Liszt, F., Ludány, A., Magyarlaki, T., Sipos, K., Berkó, G., & Tókés-Fúzesi, M. (2001). A vérplazma elektrolitjai myeloma multiplexben. Orvosi hetilap, 142(27), 1449-1453.