Plasma antioxidant capacity in dogs with naturally occurring heart diseases

C. S. Hetyey, F. Manczur, Z. Dudás-Györki, J. Reiczigel, P. Ribiczey, P. Vajdovich, K. Vörös

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The aim of the study was to compare the plasma levels of antioxidants by measuring total antioxidant activity (TAS) and ferric reducing ability of the plasma (FRAP) in healthy dogs and in those that are suffering from dilated cardiomyopathy (DCM) or from mitral endocardiosis (ME). Dogs with echocardiographically diagnosed ME (10 dogs) as well as DCM (23 dogs) were sampled. Of dogs with DCM, eight having DCM with sinus rhythm (SR) were included in the DCM-SR group and 15 having DCM with atrial fibrillation (AF) in the DCM-AF group. Total antioxidant levels measured by TAS assay differed neither significantly between the cardiac patients and the control group nor between the heart disease groups. Ferric reducing ability of the plasma in animals with cardiac disease was significantly higher than in the control animals, and the difference was also significant in between the two DCM groups. However, the differences between the antioxidant levels of the DCM and ME groups did not reach significance in none of the antioxidant (TAS and FRAP) tests. Summarizing the results of this study it can be concluded that there is an increased antioxidant reactivity detected by the FRAP, but not by the TAS assay in the blood of dogs with naturally occurring cardiac disorders. The magnitude of this increase seems to be more affected rather by the severity of the cardiac insufficiency and/or by the heart rate or rhythm disorder than by the underlying heart disease itself.

Original languageEnglish
Pages (from-to)36-39
Number of pages4
JournalJournal of Veterinary Medicine, Series A
Volume54
Issue number1
DOIs
Publication statusPublished - Feb 2007

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cardiomyopathy
Dilated Cardiomyopathy
heart diseases
Heart Diseases
Antioxidants
Dogs
antioxidants
dogs
sinuses
Atrial Fibrillation
assays
heart rate
animals
antioxidant activity
Heart Rate
Control Groups
blood

ASJC Scopus subject areas

  • veterinary(all)
  • Pathology and Forensic Medicine

Cite this

Plasma antioxidant capacity in dogs with naturally occurring heart diseases. / Hetyey, C. S.; Manczur, F.; Dudás-Györki, Z.; Reiczigel, J.; Ribiczey, P.; Vajdovich, P.; Vörös, K.

In: Journal of Veterinary Medicine, Series A, Vol. 54, No. 1, 02.2007, p. 36-39.

Research output: Contribution to journalArticle

Hetyey, C. S. ; Manczur, F. ; Dudás-Györki, Z. ; Reiczigel, J. ; Ribiczey, P. ; Vajdovich, P. ; Vörös, K. / Plasma antioxidant capacity in dogs with naturally occurring heart diseases. In: Journal of Veterinary Medicine, Series A. 2007 ; Vol. 54, No. 1. pp. 36-39.
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