Placental site trophoblastic tumor: Clinical and pathological report of two cases

Gabriella Arató, Vilmos Fülöp, Péter Degrell, Iván Szigetvári

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13 Citations (Scopus)

Abstract

Placental site trophoblastic tumor (PSTT) is the rarest disease of the gestational trophoblast. Our two cases will be interesting not only because of the rarity of the disease, but because both were recognized before operation. Since the tumor cells are lined up tightly side by side, this disease must be distinguished primarily from tumors of epithelial origin. The authors highlight that the diagnosis should rely on intense hPL-positivity as well as the ultrastructural image of the tumor. In histologically equivocal cases, the determination of hPL, hCG, and MIB-1 immunologic markers can be recommended as routinely performed morphological examinations. Serum hCG monitoring is recommended to follow the evolution of the tumor.

Original languageEnglish
Pages (from-to)292-294
Number of pages3
JournalPathology and Oncology Research
Volume6
Issue number4
DOIs
Publication statusPublished - Jan 1 2000

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Keywords

  • Choriocarcinoma
  • Immunohistology
  • Intermediate trophoblast
  • Placental trophoblastic tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Oncology
  • Cancer Research

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