Placental protein 10 (PP10) in the serum of patients with trophoblastic and nontrophoblastic gynaecological tumours

A. Tiitinen, G. N. Than, K. Iino, H. Halila, M. Seppälä

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Serum levels of placental protein 10 (PP10) were measured by radioimmunoassay in patients with trophoblastic (n=23) and non-trophoblastic (n=122) gynaecological tumours before, during and after treatment. Elevated levels (>2.0 μg/l) were found in 96% of patients with an untreated trophoblastic tumour, and in 22%, 20% and 12% of patients with endornetrial, cervical and ovarian carcinoma, respectively. After treatment the levels fell in patients with trophoblastic disease. Although PP10 may be tumour-associated in such cases, it is premature to assume any significance for PP10 as a tumour marker in clinical practice, because changes in serum hCG levels are much more informative.

Original languageEnglish
Pages (from-to)43-46
Number of pages4
JournalArchives of Gynecology and Obstetrics
Volume241
Issue number1
DOIs
Publication statusPublished - Mar 1 1987

Keywords

  • Nontrophoblastic gynaecological tumours
  • Placental protein 10
  • Trophoblastic tumours

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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