Phytohaemagglutinin‐Induced Leukocyte Migration Inhibition and Phytohaemagglutinin Skin Test for Screening the Cell‐Mediated Immune Response in Children

R. Szigeti, J. Bókay, T. Reéesz, D. Schuler

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Phytohaemagglutinin‐induced leukocyte migration inhibition was studied in 72 children and compared with phytohaemagglutinin skin testing. The methods were used for screening the cell‐mediated immune espouse. The in vitro method, which requires only 10‐ 15% of the number of migrating cells as compared with other migration techniques, proved to be more sensitive, but gave some false‐positive results when compared with other immunological parameters. Nevertheless, application of the microdroplet leukocyte migration is advantageous, used either simultaneously with the skin test, or as a single screening method in prematures, mature newborns and young infants, where application and/or evaluation of the skin tests is difficult.

Original languageEnglish
Pages (from-to)557-562
Number of pages6
JournalAllergy
Volume35
Issue number7
DOIs
Publication statusPublished - Oct 1980

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Keywords

  • PHA skin test
  • leukocyte migration inhibition by PHA
  • screening of delayed hypersensitivity

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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