Phytohaemagglutinin‐induced leukocyte migration inhibition was studied in 72 children and compared with phytohaemagglutinin skin testing. The methods were used for screening the cell‐mediated immune espouse. The in vitro method, which requires only 10‐ 15% of the number of migrating cells as compared with other migration techniques, proved to be more sensitive, but gave some false‐positive results when compared with other immunological parameters. Nevertheless, application of the microdroplet leukocyte migration is advantageous, used either simultaneously with the skin test, or as a single screening method in prematures, mature newborns and young infants, where application and/or evaluation of the skin tests is difficult.
|Number of pages||6|
|Publication status||Published - Oct 1980|
- PHA skin test
- leukocyte migration inhibition by PHA
- screening of delayed hypersensitivity
ASJC Scopus subject areas
- Immunology and Allergy