A sebgyógyulás fiziológiája. A sebellátás modern szemlélete

Translated title of the contribution: Physiology of wound healing. Modern approach to wound care

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The wound healing cascade is based on the programmed, reproducible cooperation of the cells involved in reparation, their products, further humoral factors and the intercellular stroma. The author describes the physiological events during the phases of cutaneous acute wound healing by second intention, such as coagulation, inflammation, proliferation, remodelling, takes into account the local pathophysiological processes found in chronic wounds. The author reviews the recent scientific literature on wound healing as well. Information is rapidly growing about the communication between cells and factors involved in cutaneous wound repair. Parallel control of the same step is common among physiological processes, with redundant safety mechanisms. The failure of therapeutic approaches based on single factor substitution is preclictible for the clinician, because it is yet impossible to properly orchestrate the introduction of these factors to the system. In case of chronic wounds sofar the most effective intervention into the course of wound healing can be achieved by adding complex live structures, such as in case of biotechnologically derived materials or skin transplantation.

Original languageHungarian
Pages (from-to)2267-2276
Number of pages10
JournalOrvosi Hetilap
Volume147
Issue number47
Publication statusPublished - Nov 26 2006

Fingerprint

Wound Healing
Wounds and Injuries
Physiological Phenomena
Literature
Skin
Skin Transplantation
Cell Communication
Inflammation
Safety
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A sebgyógyulás fiziológiája. A sebellátás modern szemlélete. / Juhász, I.

In: Orvosi Hetilap, Vol. 147, No. 47, 26.11.2006, p. 2267-2276.

Research output: Contribution to journalArticle

@article{e92d951daa834854971aa7511c23514a,
title = "A sebgy{\'o}gyul{\'a}s fiziol{\'o}gi{\'a}ja. A sebell{\'a}t{\'a}s modern szeml{\'e}lete",
abstract = "The wound healing cascade is based on the programmed, reproducible cooperation of the cells involved in reparation, their products, further humoral factors and the intercellular stroma. The author describes the physiological events during the phases of cutaneous acute wound healing by second intention, such as coagulation, inflammation, proliferation, remodelling, takes into account the local pathophysiological processes found in chronic wounds. The author reviews the recent scientific literature on wound healing as well. Information is rapidly growing about the communication between cells and factors involved in cutaneous wound repair. Parallel control of the same step is common among physiological processes, with redundant safety mechanisms. The failure of therapeutic approaches based on single factor substitution is preclictible for the clinician, because it is yet impossible to properly orchestrate the introduction of these factors to the system. In case of chronic wounds sofar the most effective intervention into the course of wound healing can be achieved by adding complex live structures, such as in case of biotechnologically derived materials or skin transplantation.",
keywords = "Acute wound healing, Angiogenesis, Chronic wound healing, Cutaneous wound, Epithelisation, Granulation tissue, Growth factors, Moist wound healing, Tissue engineering, Wound healing phases",
author = "I. Juh{\'a}sz",
year = "2006",
month = "11",
day = "26",
language = "Hungarian",
volume = "147",
pages = "2267--2276",
journal = "Orvosi Hetilap",
issn = "0030-6002",
publisher = "Akademiai Kiado",
number = "47",

}

TY - JOUR

T1 - A sebgyógyulás fiziológiája. A sebellátás modern szemlélete

AU - Juhász, I.

PY - 2006/11/26

Y1 - 2006/11/26

N2 - The wound healing cascade is based on the programmed, reproducible cooperation of the cells involved in reparation, their products, further humoral factors and the intercellular stroma. The author describes the physiological events during the phases of cutaneous acute wound healing by second intention, such as coagulation, inflammation, proliferation, remodelling, takes into account the local pathophysiological processes found in chronic wounds. The author reviews the recent scientific literature on wound healing as well. Information is rapidly growing about the communication between cells and factors involved in cutaneous wound repair. Parallel control of the same step is common among physiological processes, with redundant safety mechanisms. The failure of therapeutic approaches based on single factor substitution is preclictible for the clinician, because it is yet impossible to properly orchestrate the introduction of these factors to the system. In case of chronic wounds sofar the most effective intervention into the course of wound healing can be achieved by adding complex live structures, such as in case of biotechnologically derived materials or skin transplantation.

AB - The wound healing cascade is based on the programmed, reproducible cooperation of the cells involved in reparation, their products, further humoral factors and the intercellular stroma. The author describes the physiological events during the phases of cutaneous acute wound healing by second intention, such as coagulation, inflammation, proliferation, remodelling, takes into account the local pathophysiological processes found in chronic wounds. The author reviews the recent scientific literature on wound healing as well. Information is rapidly growing about the communication between cells and factors involved in cutaneous wound repair. Parallel control of the same step is common among physiological processes, with redundant safety mechanisms. The failure of therapeutic approaches based on single factor substitution is preclictible for the clinician, because it is yet impossible to properly orchestrate the introduction of these factors to the system. In case of chronic wounds sofar the most effective intervention into the course of wound healing can be achieved by adding complex live structures, such as in case of biotechnologically derived materials or skin transplantation.

KW - Acute wound healing

KW - Angiogenesis

KW - Chronic wound healing

KW - Cutaneous wound

KW - Epithelisation

KW - Granulation tissue

KW - Growth factors

KW - Moist wound healing

KW - Tissue engineering

KW - Wound healing phases

UR - http://www.scopus.com/inward/record.url?scp=34249751538&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34249751538&partnerID=8YFLogxK

M3 - Article

VL - 147

SP - 2267

EP - 2276

JO - Orvosi Hetilap

JF - Orvosi Hetilap

SN - 0030-6002

IS - 47

ER -