A natriureticus peptidcsalád élettani jellemzoi és klinikai szerepe

Translated title of the contribution: Physiology and clinical importance of the natriuretic peptide system

Gábor Szabó, János Rigó, Bálint Nagy

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In the last three decades many members of the natriuretic peptide family was isolated. The function and physiological role of these peptides are pleiotropic. All natriuretic peptides are synthesized from polypeptide precursors. Together with the sympathetic nervous system and other hormones they play key roles, like an endogenous system in the regulation of the body fluid homeostasis and blood pressure. Changes in this balance lead to dysfunction in the endothel and left ventricle, which can cause severe complications. In many cardiovascular diseases natriuretic peptides serve not only as marker for diagnosis and prognosis but they have therapeutic importance. In the last years the potential use of the elevated BNP levels for diagnosis of pre-eclampsia was examined. In our review we discuss the current understanding of molecular biology, biochemistry and clinical relevance of natriuretic peptides.

Translated title of the contributionPhysiology and clinical importance of the natriuretic peptide system
Original languageHungarian
Pages (from-to)1025-1034
Number of pages10
JournalOrvosi hetilap
Volume152
Issue number26
DOIs
Publication statusPublished - Jun 1 2011

ASJC Scopus subject areas

  • Medicine(all)

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