Amorf polimer segédanyagok fizikai öregedése II. Az öregedés nyomon követése

Translated title of the contribution: Physical ageing of amorphous polymeric excipients II. Tracking possibilities

R. Zelkó, Dorottya Kiss

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In the course of physical ageing of amorphous polymers, both macro- and microstructural changes occur in the materials. Volume and enthalpy relaxation can be considered as macrostructural aspects of ageing, and can be tracked by dilatometry and calorimetry, respectively. In dilatometric measurements, volume changes are usually traced back to the changes in the length of the examined materials. Among calorimetric methods, differential scanning calorimetry (DSC) is the most widely used technique for monitoring enthalpy changes. Considering microstructural aspects of polymer ageing, free volume plays a critical role in the interpretation of the experimental results. Changes in the size and distribution of the free volume holes can be tracked by spectroscopic methods like positron annihilation lifetime spectroscopy (PALS), electron spin resonance spectroscopy (ESR) and fluorescence spectroscopy. Other techniques, as the use of photochromic probes and labels or small angle X-ray scattering (SAXS) can be informative, as well. The morphological aspects of ageing, on the other hand, can be studied by scanning electron microscopy (SEM).

Original languageHungarian
Pages (from-to)55-63
Number of pages9
JournalActa Pharmaceutica Hungarica
Volume76
Issue number1
Publication statusPublished - 2006

Fingerprint

Excipients
Polymers
Calorimetry
Fluorescence Spectrometry
Differential Scanning Calorimetry
Electron Spin Resonance Spectroscopy
Electron Scanning Microscopy
Spectrum Analysis
X-Rays
Electrons

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Amorf polimer segédanyagok fizikai öregedése II. Az öregedés nyomon követése. / Zelkó, R.; Kiss, Dorottya.

In: Acta Pharmaceutica Hungarica, Vol. 76, No. 1, 2006, p. 55-63.

Research output: Contribution to journalArticle

@article{dc2bf278566c4dec97ef823a87815f9e,
title = "Amorf polimer seg{\'e}danyagok fizikai {\"o}reged{\'e}se II. Az {\"o}reged{\'e}s nyomon k{\"o}vet{\'e}se",
abstract = "In the course of physical ageing of amorphous polymers, both macro- and microstructural changes occur in the materials. Volume and enthalpy relaxation can be considered as macrostructural aspects of ageing, and can be tracked by dilatometry and calorimetry, respectively. In dilatometric measurements, volume changes are usually traced back to the changes in the length of the examined materials. Among calorimetric methods, differential scanning calorimetry (DSC) is the most widely used technique for monitoring enthalpy changes. Considering microstructural aspects of polymer ageing, free volume plays a critical role in the interpretation of the experimental results. Changes in the size and distribution of the free volume holes can be tracked by spectroscopic methods like positron annihilation lifetime spectroscopy (PALS), electron spin resonance spectroscopy (ESR) and fluorescence spectroscopy. Other techniques, as the use of photochromic probes and labels or small angle X-ray scattering (SAXS) can be informative, as well. The morphological aspects of ageing, on the other hand, can be studied by scanning electron microscopy (SEM).",
author = "R. Zelk{\'o} and Dorottya Kiss",
year = "2006",
language = "Hungarian",
volume = "76",
pages = "55--63",
journal = "Acta Pharmaceutica Hungarica",
issn = "0001-6659",
publisher = "Magyar Gyogyszereszeti Tarsasag",
number = "1",

}

TY - JOUR

T1 - Amorf polimer segédanyagok fizikai öregedése II. Az öregedés nyomon követése

AU - Zelkó, R.

AU - Kiss, Dorottya

PY - 2006

Y1 - 2006

N2 - In the course of physical ageing of amorphous polymers, both macro- and microstructural changes occur in the materials. Volume and enthalpy relaxation can be considered as macrostructural aspects of ageing, and can be tracked by dilatometry and calorimetry, respectively. In dilatometric measurements, volume changes are usually traced back to the changes in the length of the examined materials. Among calorimetric methods, differential scanning calorimetry (DSC) is the most widely used technique for monitoring enthalpy changes. Considering microstructural aspects of polymer ageing, free volume plays a critical role in the interpretation of the experimental results. Changes in the size and distribution of the free volume holes can be tracked by spectroscopic methods like positron annihilation lifetime spectroscopy (PALS), electron spin resonance spectroscopy (ESR) and fluorescence spectroscopy. Other techniques, as the use of photochromic probes and labels or small angle X-ray scattering (SAXS) can be informative, as well. The morphological aspects of ageing, on the other hand, can be studied by scanning electron microscopy (SEM).

AB - In the course of physical ageing of amorphous polymers, both macro- and microstructural changes occur in the materials. Volume and enthalpy relaxation can be considered as macrostructural aspects of ageing, and can be tracked by dilatometry and calorimetry, respectively. In dilatometric measurements, volume changes are usually traced back to the changes in the length of the examined materials. Among calorimetric methods, differential scanning calorimetry (DSC) is the most widely used technique for monitoring enthalpy changes. Considering microstructural aspects of polymer ageing, free volume plays a critical role in the interpretation of the experimental results. Changes in the size and distribution of the free volume holes can be tracked by spectroscopic methods like positron annihilation lifetime spectroscopy (PALS), electron spin resonance spectroscopy (ESR) and fluorescence spectroscopy. Other techniques, as the use of photochromic probes and labels or small angle X-ray scattering (SAXS) can be informative, as well. The morphological aspects of ageing, on the other hand, can be studied by scanning electron microscopy (SEM).

UR - http://www.scopus.com/inward/record.url?scp=33645027296&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645027296&partnerID=8YFLogxK

M3 - Article

C2 - 17094676

AN - SCOPUS:33645027296

VL - 76

SP - 55

EP - 63

JO - Acta Pharmaceutica Hungarica

JF - Acta Pharmaceutica Hungarica

SN - 0001-6659

IS - 1

ER -