Phylogenetic analysis reveals extensive evolution of avian paramyxovirus type 1 strains of pigeons (Columba livia) and suggests multiple species transmission

Dorina Ujvári, Eniko Wehmann, Erhard F. Kaleta, Ortrud Werner, Vladimir Savić, Éva Nagy, György Czifra, Béla Lomniczi

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

Partial sequence and residue substitution analyses of the fusion protein gene were performed for 68 strains of avian paramyxovirus type 1 of pigeons (PPMV-1), an antigenic variant of Newcastle disease virus (NDV) of chickens, derived from 16 countries between 1978 and 2002. The majority of isolates clustered into a single genetic lineage, termed VIb/1, within genotype VI of NDV strains of chickens, whereas a small number of isolates that originated in Croatia after 1995, grouped in a highly diverged lineage, termed VIb/2, indicating a separate host-switching event from that of VIb/1 strains. Four distinct subgroups of lineage VIb/1, Iraqi (IQ), early European (EU/ea), North American (NA) and recent European (EU/re) have emerged and circulated in the past decades. Subgroup EU/ea and NA strains were responsible for the main streams of infection in the 1980s, while EU/re viruses for infections in the 1990s. The degree of genetic diversity of viruses in the early phase of the epizootic suggested a prolonged infection period of the pigeon-type viruses prior to the emergence of the disease in the early 1980s. Shared derived character analysis showed a close genetic relationship to Sudanese viruses from the mid-1970, suggesting that PPMV-1 viruses could be of African origin.

Original languageEnglish
Pages (from-to)63-73
Number of pages11
JournalVirus Research
Volume96
Issue number1-2
DOIs
Publication statusPublished - Oct 2003

Keywords

  • Avian paramyxovirus type 1
  • Diversity
  • NDV
  • Phylogenetic analysis
  • Pigeons

ASJC Scopus subject areas

  • Cancer Research
  • Virology
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Phylogenetic analysis reveals extensive evolution of avian paramyxovirus type 1 strains of pigeons (Columba livia) and suggests multiple species transmission'. Together they form a unique fingerprint.

  • Cite this