Phylogenetic analysis of a transfusion-transmitted hepatitis A outbreak

Andrea Hettmann, Gabriella Juhász, Ágnes Dencs, Bálint Tresó, Erzsébet Rusvai, Éva Barabás, M. Takács

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A transfusion-associated hepatitis A outbreak was found in the first time in Hungary. The outbreak involved five cases. Parenteral transmission of hepatitis A is rare, but may occur during viraemia. Direct sequencing of nested PCR products was performed, and all the examined samples were identical in the VP1/2A region of the hepatitis A virus genome. HAV sequences found in recent years were compared and phylogenetic analysis showed that the strain which caused these cases is the same as that had spread in Hungary recently causing several hepatitis A outbreaks throughout the country.

Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalVirus Genes
Volume53
Issue number1
DOIs
Publication statusPublished - Feb 1 2017

Keywords

  • Hepatitis A
  • Outbreak
  • Phylogenetic analysis
  • Transfusion-transmitted

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Virology

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  • Cite this

    Hettmann, A., Juhász, G., Dencs, Á., Tresó, B., Rusvai, E., Barabás, É., & Takács, M. (2017). Phylogenetic analysis of a transfusion-transmitted hepatitis A outbreak. Virus Genes, 53(1), 15-20. https://doi.org/10.1007/s11262-016-1392-0